1.0 2011-09-21 00:19:06 UTC 2015-10-09 22:31:18 UTC FDB022755 Triamterene Pteridine A pteridine that is used as a mild diuretic. -- Pubchem; Triamterene is a potassium-sparing diuretic used in combination with thiazide diuretics for the treatment of hypertension. -- Wikipedia [HMDB] 6-Phenyl-2,4,7-triaminopteridine Ademin Ademine Diren Ditak Diurene Dyren Dyrenium Dytac Jatropur Noridil Noridyl Pterofen Pterophene Taturil Teriam Teridin Tri-Span Triampur Triamteren Triamterene Triamteril Triamteril complex Trispan Triteren C12H11N7 253.2626 253.107593387 6-phenylpteridine-2,4,7-triamine triamterene 396-01-0 NC1=NC(N)=C2N=C(C(N)=NC2=N1)C1=CC=CC=C1 InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19) FNYLWPVRPXGIIP-UHFFFAOYSA-N belongs to the class of organic compounds known as pteridines and derivatives. These are polycyclic aromatic compounds containing a pteridine moiety, which consists of a pyrimidine fused to a pyrazine ring to form pyrimido(4,5-b)pyrazine. Pteridines and derivatives Organic compounds Organoheterocyclic compounds Pteridines and derivatives Aromatic heteropolycyclic compounds Aminopyrazines Aminopyrimidines and derivatives Azacyclic compounds Benzene and substituted derivatives Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Organopnictogen compounds Primary amines Amine Aminopyrazine Aminopyrimidine Aromatic heteropolycyclic compound Azacycle Benzenoid Heteroaromatic compound Hydrocarbon derivative Imidolactam Monocyclic benzene moiety Organic nitrogen compound Organonitrogen compound Organopnictogen compound Primary amine Pteridine Pyrazine Pyrimidine Solid logp 1.21 ALOGPS logs -2.42 ALOGPS solubility 9.63e-01 g/l ALOGPS logp 1.11 ChemAxon pka_strongest_acidic 15.88 ChemAxon pka_strongest_basic 1.86 ChemAxon iupac 6-phenylpteridine-2,4,7-triamine ChemAxon average_mass 253.2626 ChemAxon mono_mass 253.107593387 ChemAxon smiles NC1=NC(N)=C2N=C(C(N)=NC2=N1)C1=CC=CC=C1 ChemAxon formula C12H11N7 ChemAxon inchi InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19) ChemAxon inchikey FNYLWPVRPXGIIP-UHFFFAOYSA-N ChemAxon polar_surface_area 129.62 ChemAxon refractivity 75.13 ChemAxon polarizability 25.9 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 7 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 8526 Specdb::CMs 27454 Specdb::CMs 99731 Specdb::CMs 164289 Specdb::NmrTwoD 1758 Specdb::NmrOneD 1818 Specdb::MsMs 6328 Specdb::MsMs 260235 Specdb::MsMs 260236 Specdb::MsMs 260237 Specdb::MsMs 280170 Specdb::MsMs 280171 Specdb::MsMs 280172 Specdb::MsMs 440893 Specdb::MsMs 440894 Specdb::MsMs 440895 Specdb::MsMs 444563 Specdb::MsMs 444564 Specdb::MsMs 444565 Specdb::MsMs 444566 Specdb::MsMs 444567 Specdb::MsMs 444568 Specdb::MsMs 444569 Specdb::MsMs 444570 Specdb::MsMs 444571 Specdb::MsMs 450478 Specdb::MsMs 450936 Specdb::MsMs 2228076 Specdb::MsMs 2228992 Specdb::MsMs 2230437 Specdb::MsMs 2235061 HMDB01940 DX2 #<Reference:0x000055ce32925d78> #<Reference:0x000055ce32925b48> #<Reference:0x000055ce32925968> #<Reference:0x000055ce329256e8> #<Reference:0x000055ce32925440> #<Reference:0x000055ce32925238> #<Reference:0x000055ce32925008> #<Reference:0x000055ce32924e28> #<Reference:0x000055ce32924a68> #<Reference:0x000055ce32924838> #<Reference:0x000055ce32924518>