1.0 2011-09-21 00:19:07 UTC 2015-10-09 22:31:18 UTC FDB022756 Brompheniramine Brompheniramine (also known as Bromfed, Bromfenex, and Dimetane) is an antihistamine drug of the propylamine class. It is commonly available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine; Brompheniramine (also known as Bromfed, Bromfenex, and Dimetane) is an antihistamine drug of the propylamine class. It is commonly available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine. -- Wikipedia; Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. [HMDB] [3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine 1-(P-Bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane 2-(P-Bromo-a-(2-dimethylaminoethyl)benzyl)pyridine 2-(P-Bromo-alpha-(2-dimethylaminoethyl)benzyl)pyridine 2-(P-Bromo-α-(2-dimethylaminoethyl)benzyl)pyridine 3-(4-Bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine 3-(P-Bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine Antihistamine compound Bromfeniramina Brompheniramine Maleate Brompheniraminum D-Brompheniramine Dexbromfeniramina Dexbrompheniramine Dexbrompheniramine Brompheniramine dexbrompheniramine maleate Dexbrompheniramine Maleate Salt Dexbrompheniraminum Dimetane Dimetane-Ten Dimetapp allergy Ilvin Parabromdylamine Parabromodylamine Veltane C16H19BrN2 319.239 318.073161265 [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine brompheniramine 86-22-6 CN(C)CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1 InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 ZDIGNSYAACHWNL-UHFFFAOYSA-N belongs to the class of organic compounds known as pheniramines. Pheniramines are compounds containing a pheniramine moiety, which is structurally characterized by the presence of a 2-benzylpyridine linked to an dimethyl(propyl)amine to form a dimethyl[3-phenyl-3-(pyridin-2-yl)propyl]amine skeleton. Pheniramines Organic compounds Organoheterocyclic compounds Pyridines and derivatives Pheniramines Aromatic heteromonocyclic compounds Aralkylamines Aryl bromides Azacyclic compounds Bromobenzenes Heteroaromatic compounds Hydrocarbon derivatives Organobromides Organopnictogen compounds Trialkylamines Amine Aralkylamine Aromatic heteromonocyclic compound Aryl bromide Aryl halide Azacycle Benzenoid Bromobenzene Halobenzene Heteroaromatic compound Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organobromide Organohalogen compound Organonitrogen compound Organopnictogen compound Pheniramine Tertiary aliphatic amine Tertiary amine organobromine compound pyridines Solid logp 3.63 ALOGPS logs -4.40 ALOGPS solubility 1.27e-02 g/l ALOGPS logp 3.75 ChemAxon pka_strongest_basic 9.48 ChemAxon iupac [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine ChemAxon average_mass 319.239 ChemAxon mono_mass 318.073161265 ChemAxon smiles CN(C)CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1 ChemAxon formula C16H19BrN2 ChemAxon inchi InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 ChemAxon inchikey ZDIGNSYAACHWNL-UHFFFAOYSA-N ChemAxon polar_surface_area 16.13 ChemAxon refractivity 83.67 ChemAxon polarizability 32.08 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 666 Specdb::NmrOneD 1819 Specdb::NmrTwoD 1759 Specdb::CMs 6608 Specdb::CMs 133591 Specdb::CMs 141325 Specdb::MsMs 1896 Specdb::MsMs 1897 Specdb::MsMs 1898 Specdb::MsMs 248679 Specdb::MsMs 248680 Specdb::MsMs 248681 Specdb::MsMs 268620 Specdb::MsMs 268621 Specdb::MsMs 268622 Specdb::MsMs 2817447 Specdb::MsMs 2817448 Specdb::MsMs 2817449 Specdb::MsMs 2888914 Specdb::MsMs 2888915 Specdb::MsMs 2888916 HMDB01941 Histamine H1 receptor P35367 HRH1