1.0 2011-09-21 00:19:09 UTC 2018-05-28 18:33:55 UTC FDB022759 Chlorpheniramine A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than Promethazine. -- Pubchem; Chlorphenamine or chlorpheniramine, commonly marketed as its salt chlorphenamine maleate (Chlor- Trimeton, Piriton, Chlor- Tripolon), is a first generation antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria.- wikipedia [HMDB] 1-(P-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane 1-(P-Chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine 2-[P-chloro-a-[2-(dimethylamino)Ethyl]benzyl]pyridine 2-[P-chloro-alpha-[2-(dimethylamino)Ethyl]benzyl]pyridine 2-[P-chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine 3-(P-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine Chlor-trimeton Chloropheniramine maleate Chlorophenylpyridamine Chlorphenamin Chlorphenamine chlorphenamine hydrogen maleate Chlorphenamine Maleate Chlorphenaminum chlorpheniaramine maleate Chlorpheniramine Chlorpheniramine Maleate Chlorpheniraminum Clofeniramina Clorfenamina Clorfeniramina g-(4-Chlorophenyl)-g-(2-pyridyl)propyldimethylamine g-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine gamma-(4-Chlorophenyl)-gamma-(2-pyridyl)propyldimethylamine gamma-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine Haynon Teldrin γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine γ-(4-chlorophenyl)-γ-(2-pyridyl)propyldimethylamine C16H19ClN2 274.788 274.123676325 [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine chlorpheniramine 113-92-8 CN(C)CCC(C1=CC=C(Cl)C=C1)C1=CC=CC=N1 InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 SOYKEARSMXGVTM-UHFFFAOYSA-N belongs to the class of organic compounds known as pheniramines. Pheniramines are compounds containing a pheniramine moiety, which is structurally characterized by the presence of a 2-benzylpyridine linked to an dimethyl(propyl)amine to form a dimethyl[3-phenyl-3-(pyridin-2-yl)propyl]amine skeleton. Pheniramines Organic compounds Organoheterocyclic compounds Pyridines and derivatives Pheniramines Aromatic heteromonocyclic compounds Aralkylamines Aryl chlorides Azacyclic compounds Chlorobenzenes Heteroaromatic compounds Hydrocarbon derivatives Organochlorides Organopnictogen compounds Trialkylamines Amine Aralkylamine Aromatic heteromonocyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Chlorobenzene Halobenzene Heteroaromatic compound Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organochloride Organohalogen compound Organonitrogen compound Organopnictogen compound Pheniramine Tertiary aliphatic amine Tertiary amine monochlorobenzenes pyridines tertiary amino compound Solid logp 3.74 ALOGPS logs -3.72 ALOGPS solubility 5.19e-02 g/l ALOGPS logp 3.58 ChemAxon pka_strongest_basic 9.47 ChemAxon iupac [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine ChemAxon average_mass 274.788 ChemAxon mono_mass 274.123676325 ChemAxon smiles CN(C)CCC(C1=CC=C(Cl)C=C1)C1=CC=CC=N1 ChemAxon formula C16H19ClN2 ChemAxon inchi InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 ChemAxon inchikey SOYKEARSMXGVTM-UHFFFAOYSA-N ChemAxon polar_surface_area 16.13 ChemAxon refractivity 80.85 ChemAxon polarizability 30.82 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 1822 Specdb::EiMs 554 Specdb::NmrTwoD 1762 Specdb::CMs 7378 Specdb::CMs 27384 Specdb::CMs 99732 Specdb::CMs 122054 Specdb::CMs 137831 Specdb::CMs 145565 Specdb::MsMs 1905 Specdb::MsMs 1906 Specdb::MsMs 1907 Specdb::MsMs 5650 Specdb::MsMs 253320 Specdb::MsMs 253321 Specdb::MsMs 253322 Specdb::MsMs 273261 Specdb::MsMs 273262 Specdb::MsMs 273263 Specdb::MsMs 374443 Specdb::MsMs 451111 Specdb::MsMs 451112 Specdb::MsMs 2240220 Specdb::MsMs 3041248 Specdb::MsMs 3041249 Specdb::MsMs 3041250 Specdb::MsMs 3102257 Specdb::MsMs 3102258 Specdb::MsMs 3102259 HMDB01944 #<Reference:0x00007f093c186248> #<Reference:0x00007f093c186090> #<Reference:0x00007f093c185ed8> bitter Histamine H1 receptor P35367 HRH1