1.0 2011-09-21 00:20:12 UTC 2015-07-21 06:57:23 UTC FDB022825 Norepinephrine sulfate Plasma norepinephrine sulfate increases after sympathetic nervous system activation by an exhausting incremental exercise test and remain elevated up to 2 h after exercise. (PMID: 8330610) Human platelets contribute to the formation of plasma norepinephrine sulfate by norepinephrine uptake, intraplatelet sulfoconjugation and release of norepinephrine sulfate. (PMID: 7968241) Higher concentrations of norepinephrine sulfate in portal venous than arterial plasma indicate substantial production of norepinephrine by mesenteric organs. (PMID: 8627312) Intravenously infused norepinephrine is sulfoconjugated in humans, indicating that a major part of NE is sulfoconjugated in blood or at sites easily accessible from blood. (PMID: 12020748) [HMDB] Noradrenaline sulfate Noradrenaline sulfoconjugate Noradrenaline sulphate Norepinephrine-3-O-sulfate Norepinephrine-3-O-sulphate Norepinephrine-o-sulfate Norepinephrine-O-sulphate C8H11NO6S 249.241 249.030707779 {4-[(1R)-2-amino-1-hydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid norepinephrine sulfate 77469-51-3 NC[C@H](O)C1=CC(O)=C(OS(O)(=O)=O)C=C1 InChI=1S/C8H11NO6S/c9-4-7(11)5-1-2-8(6(10)3-5)15-16(12,13)14/h1-3,7,10-11H,4,9H2,(H,12,13,14)/t7-/m0/s1 CVJMZWLHUCMEKO-ZETCQYMHSA-N belongs to the class of organic compounds known as phenylsulfates. Phenylsulfates are compounds containing a sulfuric acid group conjugated to a phenyl group. Phenylsulfates Organic compounds Organic acids and derivatives Organic sulfuric acids and derivatives Arylsulfates Aromatic homomonocyclic compounds 1,2-aminoalcohols 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Aralkylamines Aromatic alcohols Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds Phenoxy compounds Secondary alcohols Sulfuric acid monoesters 1,2-aminoalcohol 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid Alcohol Amine Aralkylamine Aromatic alcohol Aromatic homomonocyclic compound Benzenoid Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol Phenoxy compound Phenylsulfate Primary aliphatic amine Primary amine Secondary alcohol Sulfate-ester Sulfuric acid ester Sulfuric acid monoester Solid logp -1.65 ALOGPS logs -1.62 ALOGPS solubility 5.97e+00 g/l ALOGPS logp -0.97 ChemAxon pka_strongest_acidic -2.2 ChemAxon pka_strongest_basic 9.06 ChemAxon iupac {4-[(1R)-2-amino-1-hydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid ChemAxon average_mass 249.241 ChemAxon mono_mass 249.030707779 ChemAxon smiles NC[C@H](O)C1=CC(O)=C(OS(O)(=O)=O)C=C1 ChemAxon formula C8H11NO6S ChemAxon inchi InChI=1S/C8H11NO6S/c9-4-7(11)5-1-2-8(6(10)3-5)15-16(12,13)14/h1-3,7,10-11H,4,9H2,(H,12,13,14)/t7-/m0/s1 ChemAxon inchikey CVJMZWLHUCMEKO-ZETCQYMHSA-N ChemAxon polar_surface_area 130.08 ChemAxon refractivity 54.45 ChemAxon polarizability 22.16 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 90528 Specdb::MsMs 90529 Specdb::MsMs 90530 Specdb::MsMs 153705 Specdb::MsMs 153706 Specdb::MsMs 153707 Specdb::MsMs 2346662 Specdb::MsMs 2346663 Specdb::MsMs 2346664 Specdb::MsMs 2591551 Specdb::MsMs 2591552 Specdb::MsMs 2591553 Specdb::CMs 9531 Specdb::CMs 38250 Specdb::CMs 135111 Specdb::CMs 142845 Specdb::NmrOneD 109198 Specdb::NmrOneD 109199 Specdb::NmrOneD 109200 Specdb::NmrOneD 109201 Specdb::NmrOneD 109202 Specdb::NmrOneD 109203 Specdb::NmrOneD 109204 Specdb::NmrOneD 109205 Specdb::NmrOneD 109206 Specdb::NmrOneD 109207 Specdb::NmrOneD 109208 Specdb::NmrOneD 109209 Specdb::NmrOneD 109210 Specdb::NmrOneD 109211 Specdb::NmrOneD 109212 Specdb::NmrOneD 109213 Specdb::NmrOneD 109214 Specdb::NmrOneD 109215 Specdb::NmrOneD 109216 Specdb::NmrOneD 109217 HMDB02062 #<Reference:0x000055ce31e55ad8> #<Reference:0x000055ce31e55920> #<Reference:0x000055ce31e55768> #<Reference:0x000055ce31e555b0> #<Reference:0x000055ce31e553f8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823