1.0 2011-09-21 00:20:13 UTC 2015-07-21 06:57:23 UTC FDB022826 Heptacosanoic acid Heptacosanoic acid is a fatty acid found in follicular casts (the abnormal impactation of a sebaceous follicle) implicated as the preclinical lesion of acne vulgaris. (PMID: 2940302) Heptacosanoic acid is one of the fatty acids found that contribute to a significant increase in the microviscosity of erythrocyte membranes in patients affected with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). (PMID: 6874949) Heptacosanoic acid has been found in the adrenal cortex and brain, in adrenoleukodystrophy and Zellweger syndrome in humans. (PMID: 3806133) Heptacosanoic acid has been found in blood and tissues of patients with different genetic peroxisomal disorder (Refsum's disease, X-linked adrenoleukodystrophy, neonatal adrenoleukodystrophy or Zellweger syndrome). (PMID: 2474624) [HMDB] C27:0 Carbocerate Carboceric acid Heptacosanoate Heptacosanoic acid C27H54O2 410.7165 410.412380972 heptacosanoic acid heptacosanoic acid 7138-40-1 CCCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O InChI=1S/C27H54O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27(28)29/h2-26H2,1H3,(H,28,29) VXZBFBRLRNDJCS-UHFFFAOYSA-N belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms. Very long-chain fatty acids Organic compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates Aliphatic acyclic compounds Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Straight chain fatty acids Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Straight chain fatty acid Very long-chain fatty acid Straight chain fatty acids straight-chain saturated fatty acid very long-chain fatty acid Solid logp 9.98 ALOGPS logs -7.39 ALOGPS solubility 1.69e-05 g/l ALOGPS logp 11.15 ChemAxon pka_strongest_acidic 4.95 ChemAxon iupac heptacosanoic acid ChemAxon average_mass 410.7165 ChemAxon mono_mass 410.412380972 ChemAxon smiles CCCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O ChemAxon formula C27H54O2 ChemAxon inchi InChI=1S/C27H54O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27(28)29/h2-26H2,1H3,(H,28,29) ChemAxon inchikey VXZBFBRLRNDJCS-UHFFFAOYSA-N ChemAxon polar_surface_area 37.3 ChemAxon refractivity 127.69 ChemAxon polarizability 58.01 ChemAxon rotatable_bond_count 25 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 2244 Specdb::CMs 16892 Specdb::CMs 31386 Specdb::CMs 38251 Specdb::CMs 131163 Specdb::CMs 138897 Specdb::MsMs 63363 Specdb::MsMs 63364 Specdb::MsMs 63365 Specdb::MsMs 120312 Specdb::MsMs 120313 Specdb::MsMs 120314 Specdb::MsMs 2839272 Specdb::MsMs 2839273 Specdb::MsMs 2839274 Specdb::MsMs 2870282 Specdb::MsMs 2870283 Specdb::MsMs 2870284 HMDB02063 #<Reference:0x000055ce3281e948> #<Reference:0x000055ce3281e628> #<Reference:0x000055ce3281e308> #<Reference:0x000055ce3281df48> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823