| Record Information |
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| Version | 1.0 |
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| Creation date | 2011-09-21 00:22:01 UTC |
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| Update date | 2015-07-21 06:57:26 UTC |
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| Primary ID | FDB022938 |
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| Secondary Accession Numbers | Not Available |
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| Chemical Information |
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| FooDB Name | 4-Hydroxy-L-glutamic acid |
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| Description | 4-Hydroxy-L-glutamic acid is an intermediate in the metabolism of gamma-hydroxyglutamic acid. Specifically 4-Hydroxy-L-glutamic acid combines with 2-oxoglutarate to produce 4-hydroxy-2-oxoglutarate and glutamate. The reaction can be described as: 4-Hydroxy-L-glutamate + 2-Oxoglutarate <=> 4-Hydroxy-2-oxoglutarate + L-Glutamate. This reaction is catalyzed by 4-hydroxyglutamate aminotransferase (PMID 13948827). [HMDB] |
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| CAS Number | 2485-33-8 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| (2S)-2-Amino-4-hydroxypentanedioate | ChEBI | | (2S)-2-Amino-4-hydroxypentanedioic acid | Generator | | 4-Hydroxy-L-glutamate | Generator | | erythro-4-Hydroxyglutamate | HMDB | | L-erythro-4-Hydroxy-glutamate | HMDB | | L-erythro-4-Hydroxyglutamate | HMDB | | (2S)-2-amino-4-hydroxypentanedioate | hmdb | | (2S)-2-amino-4-hydroxypentanedioic acid | hmdb | | 4-hydroxy-L-glutamate | hmdb | | 4-Hydroxy-L-glutamic acid | hmdb | | erythro-4-hydroxyglutamate | hmdb | | L-erythro-4-hydroxy-glutamate | hmdb |
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| Predicted Properties | |
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| Chemical Formula | C5H7NO5 |
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| IUPAC name | (2S)-2-amino-4-hydroxypentanedioate |
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| InChI Identifier | InChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/p-2/t2-,3?/m0/s1 |
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| InChI Key | HBDWQSHEVMSFGY-SCQFTWEKSA-L |
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| Isomeric SMILES | N[C@@H](CC(O)C([O-])=O)C([O-])=O |
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| Average Molecular Weight | 161.1128 |
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| Monoisotopic Molecular Weight | 161.032422339 |
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| Classification |
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| Description | belongs to the class of organic compounds known as glutamic acid and derivatives. Glutamic acid and derivatives are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
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| Kingdom | Organic compounds |
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| Super Class | Organic acids and derivatives |
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| Class | Carboxylic acids and derivatives |
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| Sub Class | Amino acids, peptides, and analogues |
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| Direct Parent | Glutamic acid and derivatives |
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| Alternative Parents | |
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| Substituents | - Glutamic acid or derivatives
- Alpha-amino acid
- L-alpha-amino acid
- Amino fatty acid
- Hydroxy fatty acid
- Short-chain hydroxy acid
- Dicarboxylic acid or derivatives
- Fatty acyl
- Fatty acid
- 1,3-aminoalcohol
- Amino acid
- Secondary alcohol
- Carboxylic acid
- Organic nitrogen compound
- Alcohol
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Primary aliphatic amine
- Hydrocarbon derivative
- Organic oxide
- Carbonyl group
- Organopnictogen compound
- Amine
- Organic oxygen compound
- Organic anion
- Aliphatic acyclic compound
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| Molecular Framework | Aliphatic acyclic compounds |
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| External Descriptors | |
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| Ontology |
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| Ontology | No ontology term |
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| Physico-Chemical Properties - Experimental |
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| Physico-Chemical Properties - Experimental | | Property | Value | Reference |
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| Physical state | Solid | |
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| Physical Description | Not Available | |
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| Mass Composition | Not Available | |
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| Melting Point | Not Available | |
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| Boiling Point | Not Available | |
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| Experimental Water Solubility | Not Available | |
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| Experimental logP | Not Available | |
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| Experimental pKa | Not Available | |
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| Isoelectric point | Not Available | |
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| Charge | Not Available | |
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| Optical Rotation | Not Available | |
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| Spectroscopic UV Data | Not Available | |
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| Density | Not Available | |
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| Refractive Index | Not Available | |
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| Spectra |
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| Spectra | Not Available |
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| External Links |
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| ChemSpider ID | 4573749 |
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| ChEMBL ID | Not Available |
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| KEGG Compound ID | C03079 |
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| Pubchem Compound ID | 5460078 |
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| Pubchem Substance ID | Not Available |
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| ChEBI ID | 16338 |
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| Phenol-Explorer ID | Not Available |
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| DrugBank ID | Not Available |
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| HMDB ID | HMDB02273 |
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| CRC / DFC (Dictionary of Food Compounds) ID | Not Available |
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| EAFUS ID | Not Available |
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| Dr. Duke ID | Not Available |
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| BIGG ID | 1447439 |
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| KNApSAcK ID | Not Available |
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| HET ID | Not Available |
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| Food Biomarker Ontology | Not Available |
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| VMH ID | Not Available |
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| Flavornet ID | Not Available |
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| GoodScent ID | Not Available |
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| SuperScent ID | Not Available |
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| Wikipedia ID | Not Available |
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| Phenol-Explorer Metabolite ID | Not Available |
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| Duplicate IDS | Not Available |
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| Old DFC IDS | Not Available |
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| Associated Foods |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Biological Effects and Interactions |
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| Health Effects / Bioactivities | Not Available |
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| Enzymes | | Name | Gene Name | UniProt ID |
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| Aspartate aminotransferase, cytoplasmic | GOT1 | P17174 | | Aspartate aminotransferase, mitochondrial | GOT2 | P00505 |
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| Pathways | |
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| Metabolism | Not Available |
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| Biosynthesis | Not Available |
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| Organoleptic Properties |
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| Flavours | Not Available |
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| Files |
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| MSDS | Not Available |
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| References |
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| Synthesis Reference | Not Available |
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| General Reference | Not Available |
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| Content Reference | |
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