Record Information |
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Version | 1.0 |
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Creation date | 2011-09-21 00:22:01 UTC |
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Update date | 2015-07-21 06:57:26 UTC |
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Primary ID | FDB022938 |
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Secondary Accession Numbers | Not Available |
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Chemical Information |
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FooDB Name | 4-Hydroxy-L-glutamic acid |
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Description | 4-Hydroxy-L-glutamic acid is an intermediate in the metabolism of gamma-hydroxyglutamic acid. Specifically 4-Hydroxy-L-glutamic acid combines with 2-oxoglutarate to produce 4-hydroxy-2-oxoglutarate and glutamate. The reaction can be described as: 4-Hydroxy-L-glutamate + 2-Oxoglutarate <=> 4-Hydroxy-2-oxoglutarate + L-Glutamate. This reaction is catalyzed by 4-hydroxyglutamate aminotransferase (PMID 13948827). [HMDB] |
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CAS Number | 2485-33-8 |
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Structure | |
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Synonyms | Synonym | Source |
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(2S)-2-Amino-4-hydroxypentanedioate | ChEBI | (2S)-2-Amino-4-hydroxypentanedioic acid | Generator | 4-Hydroxy-L-glutamate | Generator | erythro-4-Hydroxyglutamate | HMDB | L-erythro-4-Hydroxy-glutamate | HMDB | L-erythro-4-Hydroxyglutamate | HMDB | (2S)-2-amino-4-hydroxypentanedioate | hmdb | (2S)-2-amino-4-hydroxypentanedioic acid | hmdb | 4-hydroxy-L-glutamate | hmdb | 4-Hydroxy-L-glutamic acid | hmdb | erythro-4-hydroxyglutamate | hmdb | L-erythro-4-hydroxy-glutamate | hmdb |
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Predicted Properties | |
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Chemical Formula | C5H7NO5 |
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IUPAC name | (2S)-2-amino-4-hydroxypentanedioate |
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InChI Identifier | InChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/p-2/t2-,3?/m0/s1 |
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InChI Key | HBDWQSHEVMSFGY-SCQFTWEKSA-L |
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Isomeric SMILES | N[C@@H](CC(O)C([O-])=O)C([O-])=O |
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Average Molecular Weight | 161.1128 |
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Monoisotopic Molecular Weight | 161.032422339 |
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Classification |
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Description | Belongs to the class of organic compounds known as glutamic acid and derivatives. Glutamic acid and derivatives are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
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Kingdom | Organic compounds |
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Super Class | Organic acids and derivatives |
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Class | Carboxylic acids and derivatives |
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Sub Class | Amino acids, peptides, and analogues |
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Direct Parent | Glutamic acid and derivatives |
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Alternative Parents | |
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Substituents | - Glutamic acid or derivatives
- Alpha-amino acid
- L-alpha-amino acid
- Amino fatty acid
- Hydroxy fatty acid
- Short-chain hydroxy acid
- Dicarboxylic acid or derivatives
- Fatty acyl
- Fatty acid
- 1,3-aminoalcohol
- Amino acid
- Secondary alcohol
- Carboxylic acid
- Organic nitrogen compound
- Alcohol
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Primary aliphatic amine
- Hydrocarbon derivative
- Organic oxide
- Carbonyl group
- Organopnictogen compound
- Amine
- Organic oxygen compound
- Organic anion
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Ontology |
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Ontology | No ontology term |
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Physico-Chemical Properties - Experimental |
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Physico-Chemical Properties - Experimental | Property | Value | Reference |
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Physical state | Solid | |
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Physical Description | Not Available | |
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Mass Composition | Not Available | |
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Melting Point | Not Available | |
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Boiling Point | Not Available | |
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Experimental Water Solubility | Not Available | |
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Experimental logP | Not Available | |
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Experimental pKa | Not Available | |
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Isoelectric point | Not Available | |
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Charge | Not Available | |
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Optical Rotation | Not Available | |
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Spectroscopic UV Data | Not Available | |
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Density | Not Available | |
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Refractive Index | Not Available | |
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Spectra |
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Spectra | Not Available |
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External Links |
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ChemSpider ID | 4573749 |
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ChEMBL ID | Not Available |
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KEGG Compound ID | C03079 |
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Pubchem Compound ID | 5460078 |
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Pubchem Substance ID | Not Available |
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ChEBI ID | 16338 |
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Phenol-Explorer ID | Not Available |
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DrugBank ID | Not Available |
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HMDB ID | HMDB02273 |
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CRC / DFC (Dictionary of Food Compounds) ID | Not Available |
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EAFUS ID | Not Available |
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Dr. Duke ID | Not Available |
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BIGG ID | 1447439 |
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KNApSAcK ID | Not Available |
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HET ID | Not Available |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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Flavornet ID | Not Available |
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GoodScent ID | Not Available |
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SuperScent ID | Not Available |
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Wikipedia ID | Not Available |
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Phenol-Explorer Metabolite ID | Not Available |
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Duplicate IDS | Not Available |
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Old DFC IDS | Not Available |
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Associated Foods |
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Food | Content Range | Average | Reference |
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Food | | | Reference |
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Biological Effects and Interactions |
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Health Effects / Bioactivities | Not Available |
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Enzymes | Name | Gene Name | UniProt ID |
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Aspartate aminotransferase, cytoplasmic | GOT1 | P17174 | Aspartate aminotransferase, mitochondrial | GOT2 | P00505 |
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Pathways | |
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Metabolism | Not Available |
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Biosynthesis | Not Available |
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Organoleptic Properties |
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Flavours | Not Available |
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Files |
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MSDS | Not Available |
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References |
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Synthesis Reference | Not Available |
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General Reference | Not Available |
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Content Reference | |
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