1.02011-09-21 00:22:01 UTC2015-07-21 06:57:26 UTCFDB0229384-Hydroxy-L-glutamic acid4-Hydroxy-L-glutamic acid is an intermediate in the metabolism of gamma-hydroxyglutamic acid. Specifically 4-Hydroxy-L-glutamic acid combines with 2-oxoglutarate to produce 4-hydroxy-2-oxoglutarate and glutamate. The reaction can be described as: 4-Hydroxy-L-glutamate + 2-Oxoglutarate <=> 4-Hydroxy-2-oxoglutarate + L-Glutamate. This reaction is catalyzed by 4-hydroxyglutamate aminotransferase (PMID 13948827). [HMDB](2S)-2-amino-4-hydroxypentanedioate(2S)-2-amino-4-hydroxypentanedioic acid4-hydroxy-L-glutamate4-Hydroxy-L-glutamic aciderythro-4-hydroxyglutamateL-erythro-4-hydroxy-glutamateL-erythro-4-HydroxyglutamateC5H7NO5161.1128161.032422339(2S)-2-amino-4-hydroxypentanedioateerythro-4-hydroxyglutamate2485-33-8N[C@@H](CC(O)C([O-])=O)C([O-])=OInChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/p-2/t2-,3?/m0/s1HBDWQSHEVMSFGY-SCQFTWEKSA-L belongs to the class of organic compounds known as glutamic acid and derivatives. Glutamic acid and derivatives are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.Glutamic acid and derivativesOrganic compoundsOrganic acids and derivativesCarboxylic acids and derivativesAmino acids, peptides, and analoguesAliphatic acyclic compounds1,3-aminoalcoholsAmino acidsAmino fatty acidsCarbonyl compoundsCarboxylic acidsDicarboxylic acids and derivativesHydrocarbon derivativesHydroxy fatty acidsL-alpha-amino acidsMonoalkylaminesOrganic anionsOrganic oxidesOrganopnictogen compoundsSecondary alcoholsShort-chain hydroxy acids and derivatives1,3-aminoalcoholAlcoholAliphatic acyclic compoundAlpha-amino acidAmineAmino acidAmino fatty acidCarbonyl groupCarboxylic acidDicarboxylic acid or derivativesFatty acidFatty acylGlutamic acid or derivativesHydrocarbon derivativeHydroxy fatty acidL-alpha-amino acidOrganic anionOrganic nitrogen compoundOrganic oxideOrganic oxygen compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundPrimary aliphatic aminePrimary amineSecondary alcoholShort-chain hydroxy acidL-alpha-amino acid aniondicarboxylic acid dianionSolidlogp-1.48logs0.46solubility5.65e+02 g/llogp-4.2pka_strongest_acidic1.68pka_strongest_basic9.16iupac(2S)-2-amino-4-hydroxypentanedioateaverage_mass161.1128mono_mass161.032422339smilesN[C@@H](CC(O)C([O-])=O)C([O-])=OformulaC5H7NO5inchiInChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/p-2/t2-,3?/m0/s1inchikeyHBDWQSHEVMSFGY-SCQFTWEKSA-Lpolar_surface_area126.51refractivity54.41polarizability13.35rotatable_bond_count4acceptor_count6donor_count2physiological_charge-1formal_charge-2Arginine and Proline MetabolismSMP00020map00330HMDB0227316338#<Reference:0x00005556749f5ce8>#<Reference:0x00005556749f5ab8>AnatidaeType 1specificAnatidae8830BeefaloType 1specificBos taurus X Bison bison297284BisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462Cattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930DeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984Greylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Mountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864Wild boarType 1specificSus scrofa9823Aspartate aminotransferase, cytoplasmicP17174GOT1Aspartate aminotransferase, mitochondrialP00505GOT2