1.0 2011-09-21 00:22:03 UTC 2015-10-09 22:33:28 UTC FDB022939 Methylcobalamin The name vitamin B12 is used in two different ways. In a broad sense it refers to a group of cobalt-containing compounds known as cobalamins - cyanocobalamin (an artifact formed as a result of the use of cyanide in the purification procedures), hydroxocobalamin and the two coenzyme forms of B12, methylcobalamin (MeB12) and 5-deoxyadenosylcobalamin (adenosylcobalamin - AdoB12). In a more specific way, the term B12 is used to refer to only one of these forms, cyanocobalamin, which is the principal B12 form used for foods and in nutritional supplements. B12 cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of B12 are bacteria and archaea. The total synthesis of B12 was reported in 1973 by Robert Burns Woodward, and remains one of the classic feats of total synthesis. Cyanocobalamin is a vitamin commonly known as vitamin B12 (or B12 for short). [HMDB] Algobaz Co-Methylcobalamin Hitocobamin M MeCbl Mecobalamin Methycobal Methyl cobalamine Methyl vitamin B12 Methyl-5,6-dimethylbenzimidazolylcobalamin Methyl-B12 Methylcob(III)alamin Methylcobalamin Methylcobaz C63H91CoN13O14P 1344.3823 1343.587806391 13422-55-4 C(CC(N)=O)C1C2=[N]3[Co+3]456(C)[N]7=CN(C8=CC(=C(C)C=C78)C)C7OC(C(C7O)OP([O-])(=O)OC(CNC(=O)CCC7(C(CC(N)=O)C(N4C7=C2C)C2(C(CC(N)=O)(C(CCC(N)=O)C(C(=C4[N]5=C(C(C4(CC(N)=O)C)CCC(N)=O)C=C3C1(C)C)C)=[N]62)C)C)C)C)CO InChI=1S/C62H89N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H2,63,77)(H2,64,78)(H2,65,79)(H2,66,80)(H2,67,81)(H2,68,82)(H,69,83)(H,85,86);1H3;/q-1;;+4/p-1/b54-32-;; GUIGZNJFVFPEGI-IGKGNRFDSA-M belongs to the class of organic compounds known as cobalamin derivatives. These are organic compounds containing a corrin ring, a cobalt atom, an a nucleotide moiety. Cobalamin Derivatives are actually derived from vitamin B12. Cobalamin derivatives Organic compounds Organoheterocyclic compounds Tetrapyrroles and derivatives Corrinoids Aromatic heteropolycyclic compounds Azacyclic compounds Benzenoids Benzimidazoles Carbonyl compounds Carboxamidines Fatty amides Hydrocarbon derivatives Lactams Metalloheterocyclic compounds Metallotetrapyrroles Organic cations Organic cobalt salts Organic oxides Organic phosphoric acids and derivatives Organopnictogen compounds Organotransition metal compounds Oxacyclic compounds Pentose phosphates Primary alcohols Primary carboxylic acid amides Pyrrolidines Pyrrolines Secondary alcohols Secondary carboxylic acid amides Tetrahydrofurans Transition metal alkyls Alcohol Amidine Aromatic heteropolycyclic compound Azacycle Benzenoid Benzimidazole Carbonyl group Carboxamide group Carboxylic acid amidine Carboxylic acid derivative Cobalamin Fatty acyl Fatty amide Hydrocarbon derivative Lactam Metalloheterocycle Metallotetrapyrrole skeleton Monosaccharide Organic cation Organic cobalt salt Organic metal salt Organic nitrogen compound Organic oxide Organic oxygen compound Organic phosphoric acid derivative Organic salt Organic transition metal moeity Organic transition metal salt Organometallic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pentose phosphate Primary alcohol Primary carboxylic acid amide Pyrrolidine Pyrroline Secondary alcohol Secondary carboxylic acid amide Tetrahydrofuran Transition metal alkyl Solid average_mass 1344.3823 ChemAxon mono_mass 1343.587806391 ChemAxon smiles C(CC(N)=O)C1C2=[N]3[Co+3]456(C)[N]7=CN(C8=CC(=C(C)C=C78)C)C7OC(C(C7O)OP([O-])(=O)OC(CNC(=O)CCC7(C(CC(N)=O)C(N4C7=C2C)C2(C(CC(N)=O)(C(CCC(N)=O)C(C(=C4[N]5=C(C(C4(CC(N)=O)C)CCC(N)=O)C=C3C1(C)C)C)=[N]62)C)C)C)C)CO ChemAxon formula C63H91CoN13O14P ChemAxon inchi InChI=1S/C62H89N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H2,63,77)(H2,64,78)(H2,65,79)(H2,66,80)(H2,67,81)(H2,68,82)(H,69,83)(H,85,86);1H3;/q-1;;+4/p-1/b54-32-;; ChemAxon inchikey GUIGZNJFVFPEGI-IGKGNRFDSA-M ChemAxon polar_surface_area 479.24 ChemAxon refractivity 353.78 ChemAxon polarizability 134.94 ChemAxon rotatable_bond_count 16 ChemAxon acceptor_count 0 ChemAxon donor_count 0 ChemAxon physiological_charge 2 ChemAxon formal_charge 2 ChemAxon HMDB02274 28115 #<Reference:0x000055ce31928998> #<Reference:0x000055ce319287e0> #<Reference:0x000055ce31928628> #<Reference:0x000055ce31928470> #<Reference:0x000055ce319282b8> #<Reference:0x000055ce31928100> #<Reference:0x000055ce31927f98> #<Reference:0x000055ce31927de0> #<Reference:0x000055ce31927c28> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823