1.0 2011-09-21 00:25:19 UTC 2025-11-19 02:43:19 UTC FDB023145 8-Hydroxy-deoxyguanosine 8-hydroxy-deoxyguanosine (8-OHdG) is a sensitive marker of the DNA damage due to hydroxyl radical attack at the C8 of guanine. This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion. [HMDB] 7,8-dihydro-2'-Deoxy-8-oxoguanosine 7,8-Dihydro-8-oxo-2'-deoxyguanosine 7,8-Dihydro-8-oxodeoxyguanosine 8-hydroxy-2-deoxyguanosine 8-Hydroxy-2'-deoxyguanosine 8-hydroxy-2'deoxyguanosine 8-hydroxydeoxy-guanosine 8-hydroxydeoxyguanine 8-hydroxydeoxyguanosine 8-OHdG 8-oxo-2'-Deoxyguanine 8-oxo-2'-DG 8-oxo-7-Hydrodeoxyguanosine 8-Oxo-7,8-dihydro-2'-deoxyguanosine 8-Oxo-7,8-dihydrodeoxyguanosine 8-Oxo-dG 8-Oxodg oh8dG C10H13N5O5 283.2407 283.091668551 2-amino-8-hydroxy-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one 8-hydroxy-2'-deoxyguanosine 88847-89-6 NC1=NC2=C(N=C(O)N2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1 InChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1 HCAJQHYUCKICQH-VPENINKCSA-N belongs to the class of organic compounds known as purine 2'-deoxyribonucleosides. Purine 2'-deoxyribonucleosides are compounds consisting of a purine linked to a ribose which lacks a hydroxyl group at position 2. Purine 2'-deoxyribonucleosides Organic compounds Nucleosides, nucleotides, and analogues Purine nucleosides Purine 2'-deoxyribonucleosides Aromatic heteropolycyclic compounds Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydroxypyrimidines N-substituted imidazoles Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Primary alcohols Purines and purine derivatives Secondary alcohols Tetrahydrofurans Alcohol Aromatic heteropolycyclic compound Azacycle Azole Heteroaromatic compound Hydrocarbon derivative Hydroxypyrimidine Imidazole Imidazopyrimidine N-substituted imidazole Organic nitrogen compound Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Primary alcohol Purine Purine 2'-deoxyribonucleoside Pyrimidine Secondary alcohol Tetrahydrofuran guanosines Solid logp -1.71 ALOGPS logs -1.28 ALOGPS solubility 1.48e+01 g/l ALOGPS logp -1.4 ChemAxon pka_strongest_acidic 10.09 ChemAxon pka_strongest_basic 1.59 ChemAxon iupac 2-amino-8-hydroxy-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one ChemAxon average_mass 283.2407 ChemAxon mono_mass 283.091668551 ChemAxon smiles NC1=NC2=C(N=C(O)N2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1 ChemAxon formula C10H13N5O5 ChemAxon inchi InChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1 ChemAxon inchikey HCAJQHYUCKICQH-VPENINKCSA-N ChemAxon polar_surface_area 155.22 ChemAxon refractivity 64.56 ChemAxon polarizability 25.82 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 8 ChemAxon donor_count 5 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 17061 Specdb::CMs 38572 Specdb::CMs 169824 Specdb::NmrOneD 10582 Specdb::NmrOneD 10583 Specdb::NmrOneD 10584 Specdb::NmrOneD 10585 Specdb::NmrOneD 10586 Specdb::NmrOneD 10587 Specdb::NmrOneD 10588 Specdb::NmrOneD 10589 Specdb::NmrOneD 10590 Specdb::NmrOneD 10591 Specdb::NmrOneD 10592 Specdb::NmrOneD 10593 Specdb::NmrOneD 10594 Specdb::NmrOneD 10595 Specdb::NmrOneD 10596 Specdb::NmrOneD 10597 Specdb::NmrOneD 10598 Specdb::NmrOneD 10599 Specdb::NmrOneD 10600 Specdb::NmrOneD 10601 Specdb::MsMs 101916 Specdb::MsMs 101917 Specdb::MsMs 101918 Specdb::MsMs 167610 Specdb::MsMs 167611 Specdb::MsMs 167612 Specdb::MsMs 374150 Specdb::MsMs 451836 Specdb::MsMs 2767277 Specdb::MsMs 2767278 Specdb::MsMs 2767279 Specdb::MsMs 2910725 Specdb::MsMs 2910726 Specdb::MsMs 2910727 HMDB03333 8HG #<Reference:0x000055ce327e5378> #<Reference:0x000055ce327e51c0> #<Reference:0x000055ce327e4fe0> #<Reference:0x000055ce327e4db0> #<Reference:0x000055ce327e4bd0> #<Reference:0x000055ce327e4a18> #<Reference:0x000055ce327e4860> #<Reference:0x000055ce327e46a8> #<Reference:0x000055ce327e44f0> #<Reference:0x000055ce327e4310> #<Reference:0x000055ce327e4158> #<Reference:0x000055ce327bff38> #<Reference:0x000055ce327bfd80> #<Reference:0x000055ce327bfba0> #<Reference:0x000055ce327bf830> #<Reference:0x000055ce327bf678> #<Reference:0x000055ce327bf4c0> #<Reference:0x000055ce327bf308> #<Reference:0x000055ce327bf150> #<Reference:0x000055ce327bee80> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823