1.0 2011-09-21 00:27:10 UTC 2018-05-29 01:52:58 UTC FDB023266 8Z,11Z,14Z-Eicosatrienoyl-CoA <p>8Z,11Z,14Z-eicosatrienoyl-CoA participates in the biosynthesis of unsaturated fatty acids. 8Z,11Z,14Z-eicosatrienoyl-CoA is converted from (8Z,11Z,14Z)-Icosatrienoic acid via palmitoyl-CoA hydrolase [EC:3.1.2.2].</p> <p>Unsaturated fatty acids are of similar form, except that one or more alkenyl functional groups exist along the chain, with each alkene substituting a single-bonded "-CH2-CH2-" part of the chain with a double-bonded "-CH=CH-" portion (that is, a carbon double-bonded to another carbon). The differences in geometry between the various types of unsaturated fatty acids, as well as between saturated and unsaturated fatty acids, play an important role in biological processes, and in the construction of biological structures (such as cell membranes). </p> [HMDB] (8Z,11Z,14Z)-Eicosatrienoyl-CoA (8Z,11Z,14Z)-Eicosatrienoyl-Coenzyme A C44H72N7O17P3S 1096.065 1095.391824139 (2R)-4-({[({[(2R,3R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-2-hydroxy-3,3-dimethyl-N-(2-{[2-(tricosa-8,11,14,17-tetraenoylsulfanyl)ethyl]-C-hydroxycarbonimidoyl}ethyl)butanimidic acid (2R)-4-[({[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy]-2-hydroxy-3,3-dimethyl-N-(2-{[2-(tricosa-8,11,14,17-tetraenoylsulfanyl)ethyl]-C-hydroxycarbonimidoyl}ethyl)butanimidic acid 28879-98-3 [H][C@](O)(C(=O)NCCC(=O)NCCSC(=O)CCCCCCC=CCC=CCC=CCC=CCCCCC)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@@]1([H])O[C@]([H])(C(O)[C@@]1([H])OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 InChI=1S/C44H72N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-35(53)72-28-27-46-34(52)25-26-47-42(56)39(55)44(2,3)30-65-71(62,63)68-70(60,61)64-29-33-38(67-69(57,58)59)37(54)43(66-33)51-32-50-36-40(45)48-31-49-41(36)51/h8-9,11-12,14-15,17-18,31-33,37-39,43,54-55H,4-7,10,13,16,19-30H2,1-3H3,(H,46,52)(H,47,56)(H,60,61)(H,62,63)(H2,45,48,49)(H2,57,58,59)/t33-,37?,38+,39+,43-/m1/s1 VPDGJOHYVQUGHC-VYKMITLISA-N belongs to the class of organic compounds known as 5'-deoxyribonucleosides. These are nucleosides in which the oxygen atom at the 5'position of the ribose moiety has been replaced by another atom. The nucleobases here are limited to purine, pyrimidine, and pyridine derivatives. 5'-deoxyribonucleosides Organic compounds Nucleosides, nucleotides, and analogues 5'-deoxyribonucleosides Aromatic heteropolycyclic compounds 1,2-diols 6-aminopurines Alpha amino acids Amino acids Aminopyrimidines and derivatives Azacyclic compounds Carbonyl compounds Carboxylic acids Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Monoalkylamines Monocarboxylic acids and derivatives N-substituted imidazoles Organic cations Organic oxides Organopnictogen compounds Oxacyclic compounds Pentoses Secondary alcohols Selenoethers Tetrahydrofurans 1,2-diol 5'-deoxyribonucleoside 6-aminopurine Alcohol Alpha-amino acid Alpha-amino acid or derivatives Amine Amino acid Amino acid or derivatives Aminopyrimidine Aromatic heteropolycyclic compound Azacycle Azole Carbonyl group Carboxylic acid Carboxylic acid derivative Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Imidazole Imidazopyrimidine Imidolactam Monocarboxylic acid or derivatives Monosaccharide N-glycosyl compound N-substituted imidazole Organic cation Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organoselenium compound Oxacycle Pentose monosaccharide Primary aliphatic amine Primary amine Purine Pyrimidine Secondary alcohol Selenoether Tetrahydrofuran Solid logp 4.32 ALOGPS logs -4.25 ALOGPS solubility 6.21e-02 g/l ALOGPS logp 2.52 ChemAxon pka_strongest_acidic 0.82 ChemAxon pka_strongest_basic 6.43 ChemAxon iupac (2R)-4-({[({[(2R,3R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-2-hydroxy-3,3-dimethyl-N-(2-{[2-(tricosa-8,11,14,17-tetraenoylsulfanyl)ethyl]-C-hydroxycarbonimidoyl}ethyl)butanimidic acid ChemAxon average_mass 1096.065 ChemAxon mono_mass 1095.391824139 ChemAxon smiles [H][C@](O)(C(=O)NCCC(=O)NCCSC(=O)CCCCCCC=CCC=CCC=CCC=CCCCCC)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@@]1([H])O[C@]([H])(C(O)[C@@]1([H])OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 ChemAxon formula C44H72N7O17P3S ChemAxon inchi InChI=1S/C44H72N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-35(53)72-28-27-46-34(52)25-26-47-42(56)39(55)44(2,3)30-65-71(62,63)68-70(60,61)64-29-33-38(67-69(57,58)59)37(54)43(66-33)51-32-50-36-40(45)48-31-49-41(36)51/h8-9,11-12,14-15,17-18,31-33,37-39,43,54-55H,4-7,10,13,16,19-30H2,1-3H3,(H,46,52)(H,47,56)(H,60,61)(H,62,63)(H2,45,48,49)(H2,57,58,59)/t33-,37?,38+,39+,43-/m1/s1 ChemAxon inchikey VPDGJOHYVQUGHC-VYKMITLISA-N ChemAxon polar_surface_area 370.61 ChemAxon refractivity 274.36 ChemAxon polarizability 109.91 ChemAxon rotatable_bond_count 37 ChemAxon acceptor_count 19 ChemAxon donor_count 9 ChemAxon physiological_charge -4 ChemAxon formal_charge 0 ChemAxon HMDB03947 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Acyl-coenzyme A thioesterase 2, mitochondrial P49753 ACOT2 Cytosolic acyl coenzyme A thioester hydrolase O00154 ACOT7