1.0 2011-09-21 00:28:47 UTC 2015-07-21 06:57:39 UTC FDB023365 2-O-Methylcytosine O-2-Methylcytosine is a 2-O-methylated nucleotide residue. Naturally occurring modified residues derived from canonical RNA nucleotides are present in most cellular RNAs; their detection is difficult because of their great diversity and their irregular distribution within RNA molecules. Human ribosomes contain more than 200 modified nucleotides; of these more than 100 are 2'-O-methylated. (PMID: 17673078, 7599273) [HMDB] 2-Methoxy-4-pyrimidinamine 2-Methoxy-pyrimidin-4-ylamine 4-Amino-2-methoxypyrimidine O-2-Methylcytosine O(2)Medc C5H7N3O 125.1286 125.058911861 2-methoxypyrimidin-4-amine 4-amino-2-methoxypyrimidine 3289-47-2 COC1=NC=CC(N)=N1 InChI=1S/C5H7N3O/c1-9-5-7-3-2-4(6)8-5/h2-3H,1H3,(H2,6,7,8) DHYLZDVDOQLEAQ-UHFFFAOYSA-N belongs to the class of organic compounds known as aminopyrimidines and derivatives. These are organic compounds containing an amino group attached to a pyrimidine ring. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions. Aminopyrimidines and derivatives Organic compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Aromatic heteromonocyclic compounds Alkyl aryl ethers Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Organopnictogen compounds Primary amines Alkyl aryl ether Amine Aminopyrimidine Aromatic heteromonocyclic compound Azacycle Ether Heteroaromatic compound Hydrocarbon derivative Imidolactam Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary amine aminopyrimidine aromatic ether Solid logp 0.52 ALOGPS logs -0.23 ALOGPS solubility 7.36e+01 g/l ALOGPS logp 0.34 ChemAxon pka_strongest_basic 4.91 ChemAxon iupac 2-methoxypyrimidin-4-amine ChemAxon average_mass 125.1286 ChemAxon mono_mass 125.058911861 ChemAxon smiles COC1=NC=CC(N)=N1 ChemAxon formula C5H7N3O ChemAxon inchi InChI=1S/C5H7N3O/c1-9-5-7-3-2-4(6)8-5/h2-3H,1H3,(H2,6,7,8) ChemAxon inchikey DHYLZDVDOQLEAQ-UHFFFAOYSA-N ChemAxon polar_surface_area 61.03 ChemAxon refractivity 34.15 ChemAxon polarizability 12.07 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsIr 2196 Specdb::MsIr 2197 Specdb::MsIr 2198 Specdb::CMs 15787 Specdb::CMs 136575 Specdb::CMs 144309 Specdb::NmrOneD 48162 Specdb::NmrOneD 48163 Specdb::NmrOneD 48164 Specdb::NmrOneD 48165 Specdb::NmrOneD 48166 Specdb::NmrOneD 48167 Specdb::NmrOneD 48168 Specdb::NmrOneD 48169 Specdb::NmrOneD 48170 Specdb::NmrOneD 48171 Specdb::NmrOneD 48172 Specdb::NmrOneD 48173 Specdb::NmrOneD 48174 Specdb::NmrOneD 48175 Specdb::NmrOneD 48176 Specdb::NmrOneD 48177 Specdb::NmrOneD 48178 Specdb::NmrOneD 48179 Specdb::NmrOneD 48180 Specdb::NmrOneD 48181 Specdb::MsMs 300988 Specdb::MsMs 300989 Specdb::MsMs 300990 Specdb::MsMs 343399 Specdb::MsMs 343400 Specdb::MsMs 343401 Specdb::MsMs 3045517 Specdb::MsMs 3045518 Specdb::MsMs 3045519 Specdb::MsMs 3095026 Specdb::MsMs 3095027 Specdb::MsMs 3095028 HMDB04339 #<Reference:0x000055ce33476060> #<Reference:0x000055ce33475ea8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823