1.0 2011-09-21 00:29:11 UTC 2025-11-19 02:43:56 UTC FDB023388 Formebolone Formebolone is a synthetic anabolic steroid. It is suspected of misuse in sports and therefore tested for in regular screening of athletes. The desire to artificially enhance physical performance in order to increase the chances to win in sports competition is supposedly as old as mankind itself. Already during the ancient Olympic Games, in approximately 200 B.C., athletes used concoctions of mushrooms and plant seeds, as well as special diets including bovine and canine testicles, as reported by Philostratos and Galen. The attempt to improve the power and strength of racing animals also has a long history, as it has been reported that the ancient Romans fed their horses so-called 'Hydromel', a mixture of honey and water, in order to increase endurance. The manipulation of the capacities of an athlete or animal has been referred to as doping since 1889, when this term, originating from a dialect spoken in the south-eastern region of Africa, was included in a British dictionary. With the athlete Linton, the first authentic doping-related death occurred in 1886 during a cycle race (Paris-Bordeaux), caused by an overdose of caffeine. (For a more complete review on doping see PMID: 15808003) [HMDB] (11a,17b)-11,17-dihydroxy-17-methyl-3-oxo-Androsta-1,4-diene-2-carboxaldehyde 11a,17b-dihydroxy-17-methyl-3-oxo-Androsta-1,4-diene-2-carboxaldehyde 11a,17b-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde 2-Formyl-11a-hydroxy-D1-methyltestosterone 2-Formyl-17a-methylandrosta-1,4-dien-11a,17b-diol-3-one 2-Formyl-17a-methylandrosta-1,4-diene-11a,17b-dihydroxy-3-one 2-Formyl-17a-methylandrosta-1,4-diene-11a,17b-diol-3-one Esiclene Formyldienolone C21H28O4 344.4446 344.198759384 (1S,2R,10S,11S,14S,15S,17R)-14,17-dihydroxy-2,14,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-4-carbaldehyde formebolone 2454-11-7 [H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C(C=O)=C[C@]12C InChI=1S/C21H28O4/c1-19-9-12(11-22)16(23)8-13(19)4-5-14-15-6-7-21(3,25)20(15,2)10-17(24)18(14)19/h8-9,11,14-15,17-18,24-25H,4-7,10H2,1-3H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1 AMVODTGMYSRMNP-GNIMZFFESA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Androgens and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Aliphatic homopolycyclic compounds 11-alpha-hydroxysteroids 17-hydroxysteroids 3-oxo delta-1,4-steroids Aldehydes Cyclic alcohols and derivatives Cyclic ketones Delta-1,4-steroids Hydrocarbon derivatives Organic oxides Secondary alcohols Tertiary alcohols 11-alpha-hydroxysteroid 11-hydroxysteroid 17-hydroxysteroid 3-oxo-delta-1,4-steroid 3-oxosteroid Alcohol Aldehyde Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic alcohol Cyclic ketone Delta-1,4-steroid Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Secondary alcohol Tertiary alcohol Solid logp 2.59 ALOGPS logs -3.76 ALOGPS solubility 6.05e-02 g/l ALOGPS logp 1.76 ChemAxon pka_strongest_acidic 14.39 ChemAxon pka_strongest_basic -2.9 ChemAxon iupac (1S,2R,10S,11S,14S,15S,17R)-14,17-dihydroxy-2,14,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-4-carbaldehyde ChemAxon average_mass 344.4446 ChemAxon mono_mass 344.198759384 ChemAxon smiles [H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C(C=O)=C[C@]12C ChemAxon formula C21H28O4 ChemAxon inchi InChI=1S/C21H28O4/c1-19-9-12(11-22)16(23)8-13(19)4-5-14-15-6-7-21(3,25)20(15,2)10-17(24)18(14)19/h8-9,11,14-15,17-18,24-25H,4-7,10H2,1-3H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1 ChemAxon inchikey AMVODTGMYSRMNP-GNIMZFFESA-N ChemAxon polar_surface_area 74.6 ChemAxon refractivity 96.9 ChemAxon polarizability 38.13 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 16298 Specdb::CMs 38775 Specdb::CMs 172152 Specdb::MsMs 255882 Specdb::MsMs 255883 Specdb::MsMs 255884 Specdb::MsMs 275823 Specdb::MsMs 275824 Specdb::MsMs 275825 Specdb::MsMs 2467193 Specdb::MsMs 2467194 Specdb::MsMs 2467195 Specdb::MsMs 2498540 Specdb::MsMs 2498541 Specdb::MsMs 2498542 HMDB04631 #<Reference:0x000055ce320cecb0>