1.0 2011-09-21 00:29:13 UTC 2015-07-21 06:57:41 UTC FDB023389 4-Chloromethandienone 4-Chloromethandienone is a synthetic anabolic steroid, suspected of misuse in sports. Although the widespread use of androgenic anabolic steroids might be implicated in the development of hormone-sensitive tumors, there are few reports regarding a possible causal relation between doping and cancer; however, there is one reported case of a 32-year-old man that underwent right radical orchiectomy for a tumor (identified as an intratesticular leiomyosarcoma) of the upper pole of the right testicle where the patient reported a 5-year history of systematic use of high dose of 4-Chloromethandienone. (PMID: 10526287) [HMDB] (17b)-4-chloro-17-hydroxy-17-methyl-Androsta-1,4-dien-3-one 1-Dehydro-4-chloro-17-methyltestosterone 1-Dehydro-4-chloro-17a-methyltestosterone 4-Chloro-1-dehydro-17-methyltestosterone 4-Chloro-1-dehydromethyltestosterone 4-Chloro-1,2-dehydro-17a-methyltestosterone 4-Chloro-17a-methyl-17b-hydroxyandrosta-1,4-dien-3-one 4-chloro-17b-hydroxy-17-methyl-Androsta-1,4-dien-3-one 4-Chloro-17b-hydroxy-17a-methyl-5a-androsta-1,4-dien-3-one 4-chlorodehydromethyltestosterone 4-Chlorodianabol CDMT Oral-Turinabol Turinabol-oral C20H27ClO2 334.88 334.169957815 (1S,2R,10R,11S,14S,15S)-6-chloro-14-hydroxy-2,14,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one oral turinabol 2446-23-3 [H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=C(Cl)C(=O)C=C[C@]12C InChI=1S/C20H27ClO2/c1-18-9-8-16(22)17(21)15(18)5-4-12-13(18)6-10-19(2)14(12)7-11-20(19,3)23/h8-9,12-14,23H,4-7,10-11H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1 AGUNEISBPXQOPA-XMUHMHRVSA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Androgens and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Aliphatic homopolycyclic compounds 17-hydroxysteroids 3-oxo delta-1,4-steroids Alpha-chloroketones Chloroalkenes Cyclic alcohols and derivatives Cyclic ketones Delta-1,4-steroids Halogenated steroids Hydrocarbon derivatives Organic oxides Organochlorides Tertiary alcohols Vinyl chlorides 17-hydroxysteroid 3-oxo-delta-1,4-steroid 3-oxosteroid 4-halo-steroid Alcohol Aliphatic homopolycyclic compound Alpha-chloroketone Alpha-haloketone Androgen-skeleton Carbonyl group Chloroalkene Cyclic alcohol Cyclic ketone Delta-1,4-steroid Halo-steroid Haloalkene Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organooxygen compound Oxosteroid Tertiary alcohol Vinyl chloride Vinyl halide Solid logp 4.11 ALOGPS logs -4.77 ALOGPS solubility 5.75e-03 g/l ALOGPS logp 4.03 ChemAxon pka_strongest_basic -0.53 ChemAxon iupac (1S,2R,10R,11S,14S,15S)-6-chloro-14-hydroxy-2,14,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one ChemAxon average_mass 334.88 ChemAxon mono_mass 334.169957815 ChemAxon smiles [H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=C(Cl)C(=O)C=C[C@]12C ChemAxon formula C20H27ClO2 ChemAxon inchi InChI=1S/C20H27ClO2/c1-18-9-8-16(22)17(21)15(18)5-4-12-13(18)6-10-19(2)14(12)7-11-20(19,3)23/h8-9,12-14,23H,4-7,10-11H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1 ChemAxon inchikey AGUNEISBPXQOPA-XMUHMHRVSA-N ChemAxon polar_surface_area 37.3 ChemAxon refractivity 94.95 ChemAxon polarizability 37.26 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 12443 Specdb::CMs 38776 Specdb::CMs 153796 Specdb::MsMs 293380 Specdb::MsMs 293381 Specdb::MsMs 293382 Specdb::MsMs 333847 Specdb::MsMs 333848 Specdb::MsMs 333849 Specdb::MsMs 2287818 Specdb::MsMs 2287819 Specdb::MsMs 2287820 Specdb::MsMs 2648487 Specdb::MsMs 2648488 Specdb::MsMs 2648489 HMDB04634 #<Reference:0x000055ce323c0b80>