| Record Information |
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| Version | 1.0 |
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| Creation date | 2011-09-21 00:29:23 UTC |
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| Update date | 2015-07-21 06:57:41 UTC |
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| Primary ID | FDB023402 |
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| Secondary Accession Numbers | Not Available |
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| Chemical Information |
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| FooDB Name | 11(R)-HETE |
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| Description | 11(R)-HETE is produced from arachidonic acid by both COX-1 and COX-2 (cyclooxygenases). Using a model of intestinal epithelial cells that express the COX-2 permanently, 11(R)-HETE is produced upon stimulation. However, 11(R)-HETE is not detected in intact cells. Endothelial cells release several factors which influence vascular tone, leukocyte function and platelet aggregation; 11(R)-HETE is one of these factors. (PMID: 15964853, 8555273) [HMDB] |
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| CAS Number | 73347-43-0 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| 11-HETE | hmdb | | 11-hydroxy-arachidonic acid | hmdb | | 11-hydroxyeicosatetraenoate | hmdb | | 11-hydroxyeicosatetraenoic acid | hmdb | | 11R-hydroxy-5E,8Z,12Z,14Z-eicosatetraenoate | hmdb | | 11R-hydroxy-5E,8Z,12Z,14Z-eicosatetraenoic acid | hmdb |
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| Predicted Properties | |
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| Chemical Formula | C20H32O3 |
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| IUPAC name | (11R)-11-hydroxyicosa-5,8,12,14-tetraenoic acid |
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| InChI Identifier | InChI=1S/C20H32O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)/t19-/m0/s1 |
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| InChI Key | GCZRCCHPLVMMJE-IBGZPJMESA-N |
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| Isomeric SMILES | [H][C@@](O)(CC=CCC=CCCCC(O)=O)C=CC=CCCCCC |
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| Average Molecular Weight | 320.4663 |
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| Monoisotopic Molecular Weight | 320.23514489 |
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| Classification |
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| Description | Belongs to the class of organic compounds known as hydroxyeicosatetraenoic acids. These are eicosanoic acids with an attached hydroxyl group and four CC double bonds. |
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| Kingdom | Organic compounds |
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| Super Class | Lipids and lipid-like molecules |
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| Class | Fatty Acyls |
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| Sub Class | Eicosanoids |
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| Direct Parent | Hydroxyeicosatetraenoic acids |
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| Alternative Parents | |
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| Substituents | - Hydroxyeicosatetraenoic acid
- Long-chain fatty acid
- Hydroxy fatty acid
- Fatty acid
- Unsaturated fatty acid
- Secondary alcohol
- Carboxylic acid derivative
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Organic oxide
- Organic oxygen compound
- Alcohol
- Hydrocarbon derivative
- Carbonyl group
- Organooxygen compound
- Aliphatic acyclic compound
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| Molecular Framework | Aliphatic acyclic compounds |
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| External Descriptors | Not Available |
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| Ontology |
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| Ontology | No ontology term |
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| Physico-Chemical Properties |
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| Physico-Chemical Properties - Experimental | | Property | Value | Reference |
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| Physical state | Solid | |
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| Physical Description | Not Available | |
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| Mass Composition | Not Available | |
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| Melting Point | Not Available | |
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| Boiling Point | Not Available | |
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| Experimental Water Solubility | Not Available | |
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| Experimental logP | Not Available | |
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| Experimental pKa | Not Available | |
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| Isoelectric point | Not Available | |
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| Charge | Not Available | |
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| Optical Rotation | Not Available | |
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| Spectroscopic UV Data | Not Available | |
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| Density | Not Available | |
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| Refractive Index | Not Available | |
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| Spectra |
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| Spectra | Not Available |
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| External Links |
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| ChemSpider ID | 4472406 |
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| ChEMBL ID | Not Available |
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| KEGG Compound ID | C14780 |
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| Pubchem Compound ID | 5312981 |
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| Pubchem Substance ID | Not Available |
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| ChEBI ID | 34126 |
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| Phenol-Explorer ID | Not Available |
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| DrugBank ID | Not Available |
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| HMDB ID | HMDB04682 |
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| CRC / DFC (Dictionary of Food Compounds) ID | Not Available |
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| EAFUS ID | Not Available |
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| Dr. Duke ID | Not Available |
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| BIGG ID | Not Available |
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| KNApSAcK ID | Not Available |
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| HET ID | Not Available |
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| Food Biomarker Ontology | Not Available |
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| VMH ID | Not Available |
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| Flavornet ID | Not Available |
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| GoodScent ID | Not Available |
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| SuperScent ID | Not Available |
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| Wikipedia ID | Not Available |
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| Phenol-Explorer Metabolite ID | Not Available |
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| Duplicate IDS | Not Available |
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| Old DFC IDS | Not Available |
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| Associated Foods |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Biological Effects and Interactions |
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| Health Effects / Bioactivities | Not Available |
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| Enzymes | Not Available |
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| Pathways | Not Available |
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| Metabolism | Not Available |
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| Biosynthesis | Not Available |
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| Organoleptic Properties |
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| Flavours | Not Available |
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| Files |
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| MSDS | Not Available |
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| References |
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| Synthesis Reference | Not Available |
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| General Reference | Not Available |
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| Content Reference | |
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