1.0 2011-09-21 00:29:46 UTC 2015-07-21 06:57:43 UTC FDB023424 3-Methyluridine 3-Methyluridine is a modified nucleoside of cellular RNA. All modifications are formed post-transcriptionally in RNA from the normal nucleosides by modifying enzymes, especially specific RNA-methyltransferases and RNA-synthetases. Due to the lack of specific phosphorylases for modified nucleosides they cannot be recycled for synthesizing RNA, so they are excreted quantitatively in urine. (PMID 15906010) [HMDB] 3-methyl-Uridine N-3-Methyluridine N3-Methyluridine C10H14N2O6 258.228 258.08518619 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione N-3-methyluridine 2140-69-4 CN1C(=O)C=CN(C2OC(CO)C(O)C2O)C1=O InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3 UTQUILVPBZEHTK-UHFFFAOYSA-N belongs to the class of organic compounds known as pyrimidine nucleosides. Pyrimidine nucleosides are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety. Pyrimidine nucleosides Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleosides Aromatic heteromonocyclic compounds Azacyclic compounds Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Pentoses Primary alcohols Pyrimidones Secondary alcohols Tetrahydrofurans Ureas Vinylogous amides Alcohol Aromatic heteromonocyclic compound Azacycle Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Lactam Monosaccharide N-glycosyl compound Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pentose monosaccharide Primary alcohol Pyrimidine Pyrimidine nucleoside Pyrimidone Secondary alcohol Tetrahydrofuran Urea Vinylogous amide Solid logp -1.43 ALOGPS logs -0.00 ALOGPS solubility 2.57e+02 g/l ALOGPS logp -2.2 ChemAxon pka_strongest_acidic 12.55 ChemAxon pka_strongest_basic -3 ChemAxon iupac 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ChemAxon average_mass 258.228 ChemAxon mono_mass 258.08518619 ChemAxon smiles CN1C(=O)C=CN(C2OC(CO)C(O)C2O)C1=O ChemAxon formula C10H14N2O6 ChemAxon inchi InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3 ChemAxon inchikey UTQUILVPBZEHTK-UHFFFAOYSA-N ChemAxon polar_surface_area 110.54 ChemAxon refractivity 57.46 ChemAxon polarizability 24.21 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 23359 Specdb::CMs 38809 Specdb::CMs 136442 Specdb::CMs 144176 Specdb::MsMs 95775 Specdb::MsMs 95776 Specdb::MsMs 95777 Specdb::MsMs 160113 Specdb::MsMs 160114 Specdb::MsMs 160115 Specdb::MsMs 2282191 Specdb::MsMs 2282192 Specdb::MsMs 2282193 Specdb::MsMs 3086149 Specdb::MsMs 3086150 Specdb::MsMs 3086151 Specdb::NmrOneD 48442 Specdb::NmrOneD 48443 Specdb::NmrOneD 48444 Specdb::NmrOneD 48445 Specdb::NmrOneD 48446 Specdb::NmrOneD 48447 Specdb::NmrOneD 48448 Specdb::NmrOneD 48449 Specdb::NmrOneD 48450 Specdb::NmrOneD 48451 Specdb::NmrOneD 48452 Specdb::NmrOneD 48453 Specdb::NmrOneD 48454 Specdb::NmrOneD 48455 Specdb::NmrOneD 48456 Specdb::NmrOneD 48457 Specdb::NmrOneD 48458 Specdb::NmrOneD 48459 Specdb::NmrOneD 48460 Specdb::NmrOneD 48461 HMDB04813 #<Reference:0x000055ce3214a540> #<Reference:0x000055ce3214a338> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823