1.0 2011-09-21 00:31:55 UTC 2015-10-09 22:33:11 UTC FDB023581 Lansoprazole Lansoprazole is a proton pump inhibitor similar to omeprazole which prevents the stomach from producing acid. Lansoprazole's plasma elimination half-life is not proportional to the duration of the drug's effects (i.e. gastric acid suppression). The plasma elimination half-life is 1.5 hours or less, and the effects of the drug last for over 24 hours after it has been given for 5 days or more. [HMDB] AG 1749 Agopton Amarin Aprazol Bamalite Blason Ketian Lancid Lanfast Lanproton Lansopep Lansophed Lansoprazol Lansoprazole Lansoprazolum Lansox Lanston Lanz Lanzo Lanzol Lanzopral Lanzor Lanzul Lapraz Lasoprol Limpidex Mesactol Monolitum Ogastro Opiren Prevacid C16H14F3N3O2S 369.361 369.075882012 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole lansoprazole 103577-45-3 CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1 InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22) MJIHNNLFOKEZEW-UHFFFAOYSA-N belongs to the class of organic compounds known as sulfinylbenzimidazoles. These are polycyclic aromatic compounds containing a sulfinyl group attached at the position 2 of a benzimidazole moiety. Sulfinylbenzimidazoles Organic compounds Organoheterocyclic compounds Benzimidazoles Sulfinylbenzimidazoles Aromatic heteropolycyclic compounds Alkyl aryl ethers Alkyl fluorides Azacyclic compounds Benzenoids Heteroaromatic compounds Hydrocarbon derivatives Imidazoles Methylpyridines Organic oxides Organofluorides Organonitrogen compounds Organopnictogen compounds Sulfinyl compounds Sulfoxides Alkyl aryl ether Alkyl fluoride Alkyl halide Aromatic heteropolycyclic compound Azacycle Azole Benzenoid Ether Heteroaromatic compound Hydrocarbon derivative Imidazole Methylpyridine Organic nitrogen compound Organic oxide Organic oxygen compound Organofluoride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Pyridine Sulfinyl compound Sulfinylbenzimidazole Sulfoxide benzimidazoles pyridines sulfoxide Solid logp 2.84 ALOGPS logs -3.17 ALOGPS solubility 2.50e-01 g/l ALOGPS logp 3.03 ChemAxon pka_strongest_acidic 9.35 ChemAxon pka_strongest_basic 4.16 ChemAxon iupac 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole ChemAxon average_mass 369.361 ChemAxon mono_mass 369.075882012 ChemAxon smiles CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1 ChemAxon formula C16H14F3N3O2S ChemAxon inchi InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22) ChemAxon inchikey MJIHNNLFOKEZEW-UHFFFAOYSA-N ChemAxon polar_surface_area 67.87 ChemAxon refractivity 87.61 ChemAxon polarizability 34.59 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 2017 Specdb::CMs 8360 Specdb::CMs 123605 Specdb::CMs 128682 Specdb::CMs 147849 Specdb::NmrTwoD 1952 Specdb::MsMs 2439 Specdb::MsMs 2440 Specdb::MsMs 2441 Specdb::MsMs 259305 Specdb::MsMs 259306 Specdb::MsMs 259307 Specdb::MsMs 279243 Specdb::MsMs 279244 Specdb::MsMs 279245 Specdb::MsMs 374226 Specdb::MsMs 436409 Specdb::MsMs 436410 Specdb::MsMs 436411 Specdb::MsMs 436412 Specdb::MsMs 436413 Specdb::MsMs 436414 Specdb::MsMs 436415 Specdb::MsMs 436416 Specdb::MsMs 436417 Specdb::MsMs 443794 Specdb::MsMs 443795 Specdb::MsMs 443796 Specdb::MsMs 443797 Specdb::MsMs 443798 Specdb::MsMs 443799 HMDB05008 #<Reference:0x000055ce319f68c0> #<Reference:0x000055ce319f6708> Potassium-transporting ATPase alpha chain 1 P20648 ATP4A