1.0 2011-09-21 00:31:58 UTC 2015-07-21 06:57:46 UTC FDB023584 Clopidogrel Clopidogrel is a potent oral antiplatelet agent often used in the treatment of coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix. -- Wikipedia; Clopidogrel is a potent oral antiplatelet agent often used in the treatment of coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix. It is also marketed in the generic form by Apotex, a large Canadian generic pharmaceutical company, though an injunction to withhold further shipments of their form is in effect while patent issues are dealt with. In 2005 it was the world's second highest selling pharmaceutical with sales of US$5.9 billion. [HMDB] (+)-(S)-Clopidogrel (+)-Clopidogrel (S)-Clopidogrel Clopidogrel Clopidogrel bisulfate Clopidogrel bisulphate Clopidogrelum Isocover Plavix C16H16ClNO2S 321.822 321.059027158 methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate clopidogrel 113665-84-2 [H][C@@](N1CCC2=C(C1)C=CS2)(C(=O)OC)C1=CC=CC=C1Cl InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1 GKTWGGQPFAXNFI-HNNXBMFYSA-N belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids. Alpha amino acid esters Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aromatic heteropolycyclic compounds Aralkylamines Aryl chlorides Azacyclic compounds Carbonyl compounds Chlorobenzenes Heteroaromatic compounds Hydrocarbon derivatives Methyl esters Monocarboxylic acids and derivatives Organic oxides Organochlorides Organopnictogen compounds Pyridines and derivatives Thienopyridines Thiophenes Trialkylamines Alpha-amino acid ester Amine Aralkylamine Aromatic heteropolycyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Carbonyl group Carboxylic acid ester Chlorobenzene Halobenzene Heteroaromatic compound Hydrocarbon derivative Methyl ester Monocarboxylic acid or derivatives Monocyclic benzene moiety Organic nitrogen compound Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Pyridine Tertiary aliphatic amine Tertiary amine Thienopyridine Thiophene methyl ester monochlorobenzenes thienopyridine Solid logp 3.84 ALOGPS logs -4.43 ALOGPS solubility 1.18e-02 g/l ALOGPS logp 4.03 ChemAxon pka_strongest_basic 5.14 ChemAxon iupac methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate ChemAxon average_mass 321.822 ChemAxon mono_mass 321.059027158 ChemAxon smiles [H][C@@](N1CCC2=C(C1)C=CS2)(C(=O)OC)C1=CC=CC=C1Cl ChemAxon formula C16H16ClNO2S ChemAxon inchi InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1 ChemAxon inchikey GKTWGGQPFAXNFI-HNNXBMFYSA-N ChemAxon polar_surface_area 29.54 ChemAxon refractivity 84.93 ChemAxon polarizability 33.19 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 25709 Specdb::CMs 130970 Specdb::CMs 138704 Specdb::MsMs 46551 Specdb::MsMs 46552 Specdb::MsMs 46553 Specdb::MsMs 163434 Specdb::MsMs 163435 Specdb::MsMs 163436 Specdb::MsMs 374557 Specdb::MsMs 450548 Specdb::MsMs 451811 Specdb::MsMs 2228759 Specdb::MsMs 2231199 Specdb::MsMs 2232980 Specdb::MsMs 2233553 Specdb::MsMs 2235405 Specdb::MsMs 2243317 Specdb::MsMs 2258170 Specdb::MsMs 2462140 Specdb::MsMs 2462141 Specdb::MsMs 2462142 Specdb::MsMs 2500307 Specdb::MsMs 2500308 Specdb::MsMs 2500309 HMDB05011 CGE #<Reference:0x000055ce326a5530> #<Reference:0x000055ce326a5350> #<Reference:0x000055ce326a5120> #<Reference:0x000055ce326a4f40> #<Reference:0x000055ce326a4d38> #<Reference:0x000055ce326a4b08> #<Reference:0x000055ce326a48b0> #<Reference:0x000055ce326a46d0> #<Reference:0x000055ce326a4450> #<Reference:0x000055ce326a4298> #<Reference:0x000055ce326a40b8> #<Reference:0x000055ce326a6070> #<Reference:0x000055ce326a3f78> #<Reference:0x000055ce326a3dc0> #<Reference:0x000055ce326a3c08> #<Reference:0x000055ce326a3a50> #<Reference:0x000055ce326a3898> #<Reference:0x000055ce326a36e0> #<Reference:0x000055ce326a3528> #<Reference:0x000055ce326a32d0> P-selectin P16109 SELP P2Y purinoceptor 12 Q9H244 P2RY12