1.0 2011-09-21 00:32:08 UTC 2015-07-21 06:57:47 UTC FDB023595 Rabeprazole Rabeprazole is a proton pump inhibitor sold (as its sodium salt) under the brand names Aciphex and Pariet (distributed by Janssen-Cilag); Rabeprazole is a proton pump inhibitor sold (as its sodium salt) and it is used in the treatment of gastric ulcers and GERD (or heartburn). It is taken once a day along with a full glass of water (preferable 30 min before breakfast). [HMDB] Aciphex Clofezone Habeprazole Pariet Pariets Rabeprazole sodium Sodium rabeprazole C18H21N3O3S 359.443 359.130362243 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole rabeprazole 117976-89-3 COCCCOC1=C(C)C(CS(=O)C2=NC3=CC=CC=C3N2)=NC=C1 InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21) YREYEVIYCVEVJK-UHFFFAOYSA-N belongs to the class of organic compounds known as sulfinylbenzimidazoles. These are polycyclic aromatic compounds containing a sulfinyl group attached at the position 2 of a benzimidazole moiety. Sulfinylbenzimidazoles Organic compounds Organoheterocyclic compounds Benzimidazoles Sulfinylbenzimidazoles Aromatic heteropolycyclic compounds Alkyl aryl ethers Azacyclic compounds Benzenoids Dialkyl ethers Heteroaromatic compounds Hydrocarbon derivatives Imidazoles Methylpyridines Organic oxides Organonitrogen compounds Organopnictogen compounds Sulfinyl compounds Sulfoxides Alkyl aryl ether Aromatic heteropolycyclic compound Azacycle Azole Benzenoid Dialkyl ether Ether Heteroaromatic compound Hydrocarbon derivative Imidazole Methylpyridine Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Pyridine Sulfinyl compound Sulfinylbenzimidazole Sulfoxide benzimidazoles pyridines sulfoxide Solid logp 2.04 ALOGPS logs -3.03 ALOGPS solubility 3.36e-01 g/l ALOGPS logp 2.09 ChemAxon pka_strongest_acidic 9.35 ChemAxon pka_strongest_basic 4.24 ChemAxon iupac 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole ChemAxon average_mass 359.443 ChemAxon mono_mass 359.130362243 ChemAxon smiles COCCCOC1=C(C)C(CS(=O)C2=NC3=CC=CC=C3N2)=NC=C1 ChemAxon formula C18H21N3O3S ChemAxon inchi InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21) ChemAxon inchikey YREYEVIYCVEVJK-UHFFFAOYSA-N ChemAxon polar_surface_area 77.1 ChemAxon refractivity 98.07 ChemAxon polarizability 39.64 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 11249 Specdb::CMs 117487 Specdb::CMs 172516 Specdb::MsMs 262398 Specdb::MsMs 262399 Specdb::MsMs 262400 Specdb::MsMs 282330 Specdb::MsMs 282331 Specdb::MsMs 282332 Specdb::MsMs 2464206 Specdb::MsMs 2464207 Specdb::MsMs 2464208 Specdb::MsMs 2500745 Specdb::MsMs 2500746 Specdb::MsMs 2500747 HMDB05026 8769 Potassium-transporting ATPase alpha chain 1 P20648 ATP4A Potassium-transporting ATPase subunit beta P51164 ATP4B