1.0 2011-09-21 00:32:18 UTC 2015-10-09 22:33:06 UTC FDB023605 Citalopram Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety; Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is sold under the brand-names Celexa (U.S., Forest Laboratories, Inc.), Cipramil, Seropram (Europe and Australia) and Ciazil (Australia); A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition; Citalopram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety. Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). [HMDB] Bonitrile Celexa Citadur Citalopram hydrobromide Nitalapram C20H21FN2O 324.3919 324.163791509 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile recital 59729-33-8 CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1 InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 WSEQXVZVJXJVFP-UHFFFAOYSA-N belongs to the class of organic compounds known as phenylbutylamines. Phenylbutylamines are compounds containing a phenylbutylamine moiety, which consists of a phenyl group substituted at the fourth carbon by an butan-1-amine. Phenylbutylamines Organic compounds Benzenoids Benzene and substituted derivatives Phenylbutylamines Aromatic heteropolycyclic compounds Aralkylamines Aryl fluorides Dialkyl ethers Fluorobenzenes Hydrocarbon derivatives Isocoumarans Nitriles Organofluorides Organopnictogen compounds Oxacyclic compounds Trialkylamines Amine Aralkylamine Aromatic heteropolycyclic compound Aryl fluoride Aryl halide Carbonitrile Dialkyl ether Ether Fluorobenzene Halobenzene Hydrocarbon derivative Isocoumaran Nitrile Organic nitrogen compound Organic oxygen compound Organofluoride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Phenylbutylamine Tertiary aliphatic amine Tertiary amine 2-benzofurans cyclic ether nitrile organofluorine compound tertiary amino compound Solid logp 3.58 ALOGPS logs -4.74 ALOGPS solubility 5.88e-03 g/l ALOGPS logp 3.76 ChemAxon pka_strongest_basic 9.78 ChemAxon iupac 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ChemAxon average_mass 324.3919 ChemAxon mono_mass 324.163791509 ChemAxon smiles CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1 ChemAxon formula C20H21FN2O ChemAxon inchi InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 ChemAxon inchikey WSEQXVZVJXJVFP-UHFFFAOYSA-N ChemAxon polar_surface_area 36.26 ChemAxon refractivity 94.02 ChemAxon polarizability 35.3 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 3 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 568 Specdb::NmrTwoD 1957 Specdb::CMs 10912 Specdb::CMs 124990 Specdb::CMs 131650 Specdb::CMs 139384 Specdb::NmrOneD 2022 Specdb::MsMs 61683 Specdb::MsMs 61684 Specdb::MsMs 61685 Specdb::MsMs 118257 Specdb::MsMs 118258 Specdb::MsMs 118259 Specdb::MsMs 441061 Specdb::MsMs 441062 Specdb::MsMs 441063 Specdb::MsMs 441064 Specdb::MsMs 441065 Specdb::MsMs 443252 Specdb::MsMs 443253 Specdb::MsMs 443254 Specdb::MsMs 443255 Specdb::MsMs 443256 Specdb::MsMs 443257 Specdb::MsMs 443258 Specdb::MsMs 443259 Specdb::MsMs 443260 Specdb::MsMs 443261 Specdb::MsMs 443262 Specdb::MsMs 443263 Specdb::MsMs 443264 Specdb::MsMs 443265 HMDB05038 #<Reference:0x000055ce31a55488> #<Reference:0x000055ce31a552d0> #<Reference:0x000055ce31a55118> #<Reference:0x000055ce31a54f60> #<Reference:0x000055ce31a54da8> #<Reference:0x000055ce31a54bf0> #<Reference:0x000055ce31a54a38> #<Reference:0x000055ce31a54880> #<Reference:0x000055ce31a546c8> #<Reference:0x000055ce31a54510> #<Reference:0x000055ce31a54358> #<Reference:0x000055ce31a541a0> #<Reference:0x000055ce31a53f98> #<Reference:0x000055ce31a53de0> #<Reference:0x000055ce31a53c28> #<Reference:0x000055ce31a53a70> #<Reference:0x000055ce31a538b8> #<Reference:0x000055ce31a53700> #<Reference:0x000055ce31a53548> Cytochrome P450 2D6 Q6NWU0 CYP2D6 Cytochrome P450, family 1, subfamily A, polypeptide 1 A0N0X8 CYP1A1