Record Information
Version1.0
Creation date2011-09-21 00:37:01 UTC
Update date2015-07-21 06:57:56 UTC
Primary IDFDB023932
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameLysoSM(d18:1)
DescriptionD-erythro-sphingosylphosphorylcholine is an intermediate in Sphingolipid metabolism. D-erythro-sphingosylphosphorylcholine is the 5th to last step in the synthesis of Digalactosylceramidesulfate and is converted from Sphingosine via the enzyme sphingosine cholinephosphotransferase ( EC 2.7.8.10). It is then converted to Sphingomyelin via the enzyme sphingosine N-acyltransferase (EC 2.3.1.24). [HMDB]
CAS Number1670-26-4
Structure
Thumb
Synonyms
SynonymSource
Sphing-4-enine-1-phosphocholineChEBI
Sphingosyl-phosphocholineChEBI
SphingosylphosphocholineChEBI
C18-Sphingosine phosphocholineHMDB
D-Erythro-sphingosylphosphorylcholineHMDB
LysosphingomyelinHMDB
SM(D18:1/0:0)HMDB
Sphingenyl-1-phosphorylcholineHMDB
Sphingomyelin(D18:1/0:0)HMDB
Sphingosine phosphorylcholineHMDB
SphingosylphosphorylcholineHMDB
C18-Sphingosine ocholineHMDB
D-erythro-SphingosylorylcholineHMDB
D-erythro-sphingosylphosphorylcholinehmdb
SM(d18:1/0:0)hmdb
Sphing-4-enine-1-ocholineChEBI
sphing-4-enine-1-phosphocholinehmdb
Sphingenyl-1-orylcholineHMDB
Sphingomyelin(d18:1/0:0)hmdb
Sphingosyl-ocholineChEBI
SphingosylocholineChEBI
Sphingosylocholine acidChEBI
Predicted Properties
PropertyValueSource
Water Solubility0.00084 g/LALOGPS
logP1.3ALOGPS
logP-0.24ChemAxon
logS-5.8ALOGPS
pKa (Strongest Acidic)1.83ChemAxon
pKa (Strongest Basic)9.68ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area102.01 ŲChemAxon
Rotatable Bond Count21ChemAxon
Refractivity141.18 m³·mol⁻¹ChemAxon
Polarizability55.37 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaC23H50N2O5P
IUPAC name{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}[2-(trimethylazaniumyl)ethoxy]phosphinic acid
InChI IdentifierInChI=1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)22(24)21-30-31(27,28)29-20-19-25(2,3)4/h17-18,22-23,26H,5-16,19-21,24H2,1-4H3/p+1/b18-17+/t22-,23+/m0/s1
InChI KeyJLVSPVFPBBFMBE-HXSWCURESA-O
Isomeric SMILESCCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C
Average Molecular Weight465.6273
Monoisotopic Molecular Weight465.345734232
Classification
Description belongs to the class of organic compounds known as sphingosylphosphorylcholines. These are sphingolipids containing a sphingosine attached to the phosphate group of a phosphocholine.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSphingolipids
Sub ClassPhosphosphingolipids
Direct ParentSphingosylphosphorylcholines
Alternative Parents
Substituents
  • Sphingosylphosphorylcholine
  • Phosphocholine
  • Phosphoethanolamine
  • Dialkyl phosphate
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Tetraalkylammonium salt
  • Quaternary ammonium salt
  • Secondary alcohol
  • Alcohol
  • Amine
  • Organic salt
  • Hydrocarbon derivative
  • Primary amine
  • Organic oxide
  • Organopnictogen compound
  • Organic oxygen compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organic nitrogen compound
  • Primary aliphatic amine
  • Organic cation
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
Physiological effect

Organoleptic effect:

Disposition

Route of exposure:

Source:

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Process

Naturally occurring process:

Role

Industrial application:

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Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positivesplash10-00ej-9782140000-24f3d9fcbb4a3475e571JSpectraViewer
ChemSpider ID4444221
ChEMBL IDNot Available
KEGG Compound IDC03640
Pubchem Compound ID5280613
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB06482
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG ID2704995
KNApSAcK IDNot Available
HET IDSPU
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
Enzymes
NameGene NameUniProt ID
Sphingomyelin phosphodiesteraseSMPD1P17405
Non-lysosomal glucosylceramidaseGBA2Q9HCG7
Proactivator polypeptidePSAPP07602
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference