1.0 2011-09-21 01:37:56 UTC 2018-05-29 01:54:29 UTC FDB028322 Adenosine 2'-phosphate Adenosine 2'-phosphate is converted enzymatically from adenosine 2',3'-cyclic phosphate via the enzyme 2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37). In the brain, this enzyme acts on 2',3'-cyclic AMP more rapidly than on the UMP or CMP derivatives. In the liver, this enzyme acts on 2',3'-cyclic CMP more rapidly than on the purine derivatives; it also hydrolyses the corresponding 3',5'-cyclic phosphates, more slowly. This latter enzyme has been called cyclic-CMP phosphodiesterase. (KEGG) This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase. [HMDB] 2'-Adenylic acid Adenosine-2'-monoate Adenosine-2'-monophosphate AMP 2'-ate AMP 2'-phosphate C10H14N5O7P 347.2212 347.063084339 {[(3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid [(3R,4R,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxyphosphonic acid 130-49-4 NC1=NC=NC2=C1N=CN2C1O[C@H](CO)[C@@H](O)[C@H]1OP(O)(O)=O InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10?/m1/s1 QDFHPFSBQFLLSW-VTHZCTBJSA-N belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Pentose phosphates Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Aromatic heteropolycyclic compounds 6-aminopurines Aminopyrimidines and derivatives Azacyclic compounds Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Monoalkyl phosphates N-substituted imidazoles Organic oxides Organopnictogen compounds Oxacyclic compounds Primary alcohols Primary amines Secondary alcohols Tetrahydrofurans 6-aminopurine Alcohol Alkyl phosphate Amine Aminopyrimidine Aromatic heteropolycyclic compound Azacycle Azole Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Imidazole Imidazopyrimidine Imidolactam Monoalkyl phosphate N-glycosyl compound N-substituted imidazole Organic nitrogen compound Organic oxide Organic phosphoric acid derivative Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Oxacycle Pentose phosphate Phosphoric acid ester Primary alcohol Primary amine Purine Pyrimidine Secondary alcohol Tetrahydrofuran Solid logp -3.13 ALOGPS logs -2.00 ALOGPS solubility 3.51e+00 g/l ALOGPS logp -4.8 ChemAxon pka_strongest_acidic 0.69 ChemAxon pka_strongest_basic 4.91 ChemAxon iupac {[(3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid ChemAxon average_mass 347.2212 ChemAxon mono_mass 347.063084339 ChemAxon smiles NC1=NC=NC2=C1N=CN2C1O[C@H](CO)[C@@H](O)[C@H]1OP(O)(O)=O ChemAxon formula C10H14N5O7P ChemAxon inchi InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10?/m1/s1 ChemAxon inchikey QDFHPFSBQFLLSW-VTHZCTBJSA-N ChemAxon polar_surface_area 186.07 ChemAxon refractivity 74.07 ChemAxon polarizability 29.37 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 10 ChemAxon donor_count 5 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 15928 Specdb::CMs 39721 Specdb::CMs 147676 Specdb::MsMs 301270 Specdb::MsMs 301271 Specdb::MsMs 301272 Specdb::MsMs 343750 Specdb::MsMs 343751 Specdb::MsMs 343752 Specdb::MsMs 3049682 Specdb::MsMs 3049683 Specdb::MsMs 3049684 Specdb::MsMs 3117890 Specdb::MsMs 3117891 Specdb::MsMs 3117892 Specdb::NmrOneD 93532 Specdb::NmrOneD 93533 Specdb::NmrOneD 93534 Specdb::NmrOneD 93535 Specdb::NmrOneD 93536 Specdb::NmrOneD 93537 Specdb::NmrOneD 93538 Specdb::NmrOneD 93539 Specdb::NmrOneD 93540 Specdb::NmrOneD 93541 Specdb::NmrOneD 93542 Specdb::NmrOneD 93543 Specdb::NmrOneD 93544 Specdb::NmrOneD 93545 Specdb::NmrOneD 93546 Specdb::NmrOneD 93547 Specdb::NmrOneD 93548 Specdb::NmrOneD 93549 Specdb::NmrOneD 93550 Specdb::NmrOneD 93551 HMDB11617 28223 #<Reference:0x000055ce307d71d0> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 2',3'-cyclic-nucleotide 3'-phosphodiesterase P09543 CNP