1.0 2011-09-21 01:38:01 UTC 2018-05-29 01:54:29 UTC FDB028327 Dimethylarsinate Cacodylic acid is the chemical compound with the formula (CH3)2AsO2H. Derivatives of cacodylic acid, cacodylates, were frequently used as herbicides. For example, "Agent Blue," one of the chemicals used during the Vietnam War, is a mixture of cacodylic acid and sodium cacodylate. Sodium cacodylate is frequently used as a buffering agent in the preparation and fixation of biological samples for transmission electron microscopy. Cacodylic acid is highly toxic by ingestion, inhalation, or skin contact. Once thought to be a byproduct of inorganic arsenic detoxification, it is now believed to have serious health consequences of its own. It has been shown to be teratogenic in rodents, most often causing cleft palate but also fetal fatality at high doses. It has been shown to be genotoxic in human cells, causing apoptosis and also decreased DNA production and shorter DNA strands. While not itself a strong carcinogen, cacodylic acid does promote tumors in the presence of carcinogens in organs such as the kidneys and liver. [HMDB] [As(CH3)2O2](-) Ansar Arsan Arsecodile Bolate Bolls Cacodylate CACODYLATE ion Cacodylic acid CACODYLic acid ion Chexmate dimethylarsinate Dimethylarsinic acid DMA DMAA Erase Hydroxydimethylarsine oxide Kakodylat Me2aso2(-) Moncide Phytar Phytar 560 Silvisar C2H6AsO2 136.9894 136.958375853 dimethylarsinate cacodylate ion 15132-04-4 C[As](C)([O-])=O InChI=1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)/p-1 OGGXGZAMXPVRFZ-UHFFFAOYSA-M belongs to the class of organic compounds known as pentaorganoarsanes. These are organoarsenic compounds containing an arsenic compound that is pentasubstituted by only organic groups. Pentaorganoarsanes Organic compounds Organometallic compounds Organometalloid compounds Organoarsenic compounds Aliphatic acyclic compounds Alkylarsine oxides Hydrocarbon derivatives Organic anions Organic metalloid salts Organic oxides Organopnictogen compounds Aliphatic acyclic compound Alkylarsine oxide Hydrocarbon derivative Organic anion Organic metalloid salt Organic oxide Organic oxygen compound Organic salt Organopnictogen compound Oxygen-containing organoarsenic compound Pentaorganoarsane a small molecule arsenic oxoanion Solid logp -0.07 ALOGPS logs -0.24 ALOGPS solubility 9.02e+01 g/l ALOGPS logp -0.33 ChemAxon pka_strongest_acidic 6.22 ChemAxon iupac dimethylarsinate ChemAxon average_mass 136.9894 ChemAxon mono_mass 136.958375853 ChemAxon smiles C[As](C)([O-])=O ChemAxon formula C2H6AsO2 ChemAxon inchi InChI=1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)/p-1 ChemAxon inchikey OGGXGZAMXPVRFZ-UHFFFAOYSA-M ChemAxon polar_surface_area 40.13 ChemAxon refractivity 14.78 ChemAxon polarizability 8.91 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge -1 ChemAxon formal_charge -1 ChemAxon Specdb::MsMs 259356 Specdb::MsMs 259357 Specdb::MsMs 259358 Specdb::MsMs 279294 Specdb::MsMs 279295 Specdb::MsMs 279296 HMDB11625 29839 CAC