1.0 2011-09-21 01:38:39 UTC 2015-07-21 06:59:23 UTC FDB028365 Galactose-beta-1,4-xylose Galactose-beta-1,4-xylose is a disaccharide and a likely degradation product from glycosaminoglycans (GAGs) such as heparin sulfate and condroitin sulfate. GAGs are a major component of proteoglycans, which typically consist of a core protein and negatively charged GAGs. Proteoglycans are widely expressed on the cell surface and in the extracellular matrix of various tissues and play important roles in the control of growth and differentiation. The biosynthesis of GAG is initiated by the formation of the linkage tetrasaccharide structure, GlcA1,3Gal1, 3Gal1,4Xyl1-O-Ser, which is common to heparin sulfate, dermatan sulfate and condroitin sulfate. In humans proteoglycan 1,4-galactosyltransferase I (Beta 1,4-galactosyltransferase 7) (B4GalTI) transfers galactose to protein-linked xylose to form galactose-beta-1,4-xylose, which is the disaccharide unit from which the last two galactosyl and glucuronosyl units of the tetrasaccharide unit are attached via transferases. [HMDB] Galactose-b-1,4-xylose Galactose-beta-1,4-xylose Galactosyl-1,4-xylose C11H20O10 312.2705 312.10564686 (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(3R,4R,5R,6R)-4,5,6-trihydroxyoxan-3-yl]oxy}oxane-3,4,5-triol (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(3R,4R,5R,6R)-4,5,6-trihydroxyoxan-3-yl]oxy}oxane-3,4,5-triol OC[C@H]1O[C@@H](O[C@@H]2CO[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O InChI=1S/C11H20O10/c12-1-3-5(13)7(15)9(17)11(20-3)21-4-2-19-10(18)8(16)6(4)14/h3-18H,1-2H2/t3-,4-,5+,6+,7+,8-,9-,10-,11+/m1/s1 VCTBNHVCBSUQPG-YOUNRWHRSA-N belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond. O-glycosyl compounds Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Aliphatic heteromonocyclic compounds Acetals Disaccharides Hemiacetals Hydrocarbon derivatives Oxacyclic compounds Oxanes Polyols Primary alcohols Secondary alcohols Acetal Alcohol Aliphatic heteromonocyclic compound Disaccharide Hemiacetal Hydrocarbon derivative O-glycosyl compound Organoheterocyclic compound Oxacycle Oxane Polyol Primary alcohol Secondary alcohol Solid logp -2.96 ALOGPS logs 0.27 ALOGPS solubility 5.87e+02 g/l ALOGPS logp -4.1 ChemAxon pka_strongest_acidic 11.26 ChemAxon pka_strongest_basic -3 ChemAxon iupac (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(3R,4R,5R,6R)-4,5,6-trihydroxyoxan-3-yl]oxy}oxane-3,4,5-triol ChemAxon average_mass 312.2705 ChemAxon mono_mass 312.10564686 ChemAxon smiles OC[C@H]1O[C@@H](O[C@@H]2CO[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O ChemAxon formula C11H20O10 ChemAxon inchi InChI=1S/C11H20O10/c12-1-3-5(13)7(15)9(17)11(20-3)21-4-2-19-10(18)8(16)6(4)14/h3-18H,1-2H2/t3-,4-,5+,6+,7+,8-,9-,10-,11+/m1/s1 ChemAxon inchikey VCTBNHVCBSUQPG-YOUNRWHRSA-N ChemAxon polar_surface_area 169.3 ChemAxon refractivity 62.37 ChemAxon polarizability 28.9 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 10 ChemAxon donor_count 7 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 310438 Specdb::MsMs 310439 Specdb::MsMs 310440 Specdb::MsMs 355159 Specdb::MsMs 355160 Specdb::MsMs 355161 Specdb::MsMs 2816374 Specdb::MsMs 2816375 Specdb::MsMs 2816376 Specdb::MsMs 2892782 Specdb::MsMs 2892783 Specdb::MsMs 2892784 Specdb::NmrOneD 150970 Specdb::NmrOneD 150971 Specdb::NmrOneD 150972 Specdb::NmrOneD 150973 Specdb::NmrOneD 150974 Specdb::NmrOneD 150975 Specdb::NmrOneD 150976 Specdb::NmrOneD 150977 Specdb::NmrOneD 150978 Specdb::NmrOneD 150979 Specdb::NmrOneD 150980 Specdb::NmrOneD 150981 Specdb::NmrOneD 150982 Specdb::NmrOneD 150983 Specdb::NmrOneD 150984 Specdb::NmrOneD 150985 Specdb::NmrOneD 150986 Specdb::NmrOneD 150987 Specdb::NmrOneD 150988 Specdb::NmrOneD 150989 Specdb::CMs 19958 Specdb::CMs 39760 Specdb::CMs 134905 Specdb::CMs 142639 Specdb::CMs 147135 Specdb::CMs 147137 Specdb::CMs 147139 Specdb::CMs 147141 Specdb::CMs 147143 Specdb::CMs 147145 Specdb::CMs 147147 Specdb::CMs 147149 Specdb::CMs 147151 Specdb::CMs 147153 Specdb::CMs 147155 Specdb::CMs 147157 Specdb::CMs 279585 HMDB11677 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columba 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 Animal Capra aegagrus hircus 9925 Domestic pig Type 1 Animal Sus scrofa domesticus 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus cuniculus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus hemionus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823