1.0 2011-09-21 01:47:25 UTC 2015-07-21 06:59:34 UTC FDB028927 UDP-L-iduronate UDP-L-iduronate is converted from UDP-n-glucuronic acid. n-Iduronic and n-glucuronic acid have been identified as the hexuronic acid components of dermatan sulfate. UDP-Dglucose is the metabolic precursor of both uranic acids . Conversion of UDP-u-glucose to UDP-n-glucuronic acid and the subsequent C-5 inversion of UDP-n-glucuronic acid to UDP-Liduronic acid is catalyzed by extracts of mammalian tissues. However, UDP-n-iduronic acid has never been isolated and its role in the polymerization of L-iduronic acid-containing polymers has remained hypothetical. [HMDB] UDP-L-iduronic acid C15H22N2O18P2 580.2853 580.034284934 (2R,3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid (2R,3S,4S,5R,6R)-6-[({[(2R,3S,4R,5R)-5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11-,12-,14-/m1/s1 HDYANYHVCAPMJV-NTWGTYGRSA-N belongs to the class of organic compounds known as pyrimidine nucleotide sugars. These are pyrimidine nucleotides bound to a saccharide derivative through the terminal phosphate group. Pyrimidine nucleotide sugars Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleotides Pyrimidine nucleotide sugars Aromatic heteromonocyclic compounds Azacyclic compounds Beta hydroxy acids and derivatives Carbonyl compounds Carboxylic acids Glucuronic acid derivatives Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Monoalkyl phosphates Monocarboxylic acids and derivatives Monosaccharide phosphates Organic oxides Organic pyrophosphates Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Oxanes Pentose phosphates Polyols Pyrans Pyrimidine ribonucleoside diphosphates Pyrimidones Secondary alcohols Tetrahydrofurans Ureas Vinylogous amides Alcohol Alkyl phosphate Aromatic heteromonocyclic compound Azacycle Beta-hydroxy acid Carbonyl group Carboxylic acid Carboxylic acid derivative Glucuronic acid or derivatives Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Hydroxy acid Lactam Monoalkyl phosphate Monocarboxylic acid or derivatives Monosaccharide Monosaccharide phosphate N-glycosyl compound Organic nitrogen compound Organic oxide Organic oxygen compound Organic phosphoric acid derivative Organic pyrophosphate Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Oxane Pentose phosphate Pentose-5-phosphate Phosphoric acid ester Polyol Pyran Pyrimidine Pyrimidine nucleotide sugar Pyrimidine ribonucleoside diphosphate Pyrimidone Secondary alcohol Tetrahydrofuran Urea Vinylogous amide Solid logp -1.21 ALOGPS logs -1.51 ALOGPS solubility 1.81e+01 g/l ALOGPS logp -4.7 ChemAxon pka_strongest_acidic 1.72 ChemAxon pka_strongest_basic -3.7 ChemAxon iupac (2R,3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid ChemAxon average_mass 580.2853 ChemAxon mono_mass 580.034284934 ChemAxon smiles O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O ChemAxon formula C15H22N2O18P2 ChemAxon inchi InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11-,12-,14-/m1/s1 ChemAxon inchikey HDYANYHVCAPMJV-NTWGTYGRSA-N ChemAxon polar_surface_area 308.61 ChemAxon refractivity 106.32 ChemAxon polarizability 45.14 ChemAxon rotatable_bond_count 9 ChemAxon acceptor_count 15 ChemAxon donor_count 9 ChemAxon physiological_charge -3 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 307909 Specdb::MsMs 307910 Specdb::MsMs 307911 Specdb::MsMs 351961 Specdb::MsMs 351962 Specdb::MsMs 351963 Specdb::MsMs 2283007 Specdb::MsMs 2283008 Specdb::MsMs 2283009 Specdb::MsMs 3085240 Specdb::MsMs 3085241 Specdb::MsMs 3085242 Specdb::CMs 18870 Specdb::CMs 39908 Specdb::CMs 282534 Specdb::CMs 392486 Specdb::CMs 392487 Specdb::CMs 392488 Specdb::CMs 392489 Specdb::CMs 392490 Specdb::CMs 392491 Specdb::CMs 392492 Specdb::CMs 392493 Specdb::CMs 392494 Specdb::CMs 392495 Specdb::CMs 392496 Specdb::CMs 392497 Specdb::CMs 392498 Specdb::CMs 392499 Specdb::CMs 392500 Specdb::CMs 392501 Specdb::CMs 392502 Specdb::CMs 392503 Specdb::CMs 392504 Specdb::CMs 392505 Specdb::CMs 392506 Specdb::CMs 392507 Specdb::NmrOneD 97198 Specdb::NmrOneD 97199 Specdb::NmrOneD 97200 Specdb::NmrOneD 97201 Specdb::NmrOneD 97202 Specdb::NmrOneD 97203 Specdb::NmrOneD 97204 Specdb::NmrOneD 97205 Specdb::NmrOneD 97206 Specdb::NmrOneD 97207 Specdb::NmrOneD 97208 Specdb::NmrOneD 97209 Specdb::NmrOneD 97210 Specdb::NmrOneD 97211 Specdb::NmrOneD 97212 Specdb::NmrOneD 97213 Specdb::NmrOneD 97214 Specdb::NmrOneD 97215 Specdb::NmrOneD 97216 Specdb::NmrOneD 97217 HMDB12304 17683 #<Reference:0x000055ce32921480> #<Reference:0x000055ce329212c8> #<Reference:0x000055ce32921098> #<Reference:0x000055ce32920e68> #<Reference:0x000055ce32920b70> #<Reference:0x000055ce329209b8> #<Reference:0x000055ce32920800> #<Reference:0x000055ce32920648> #<Reference:0x000055ce32920490> #<Reference:0x000055ce32920288> #<Reference:0x000055ce32920080> #<Reference:0x000055ce3291fcc0> #<Reference:0x000055ce3291f838> #<Reference:0x000055ce3291f298> #<Reference:0x000055ce3291ee88> #<Reference:0x000055ce3291e988> #<Reference:0x000055ce3291e488> #<Reference:0x000055ce3291e2a8> #<Reference:0x000055ce3291e0f0> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 UDP-glucuronosyltransferase 1-1 P22309 UGT1A1 UDP-glucuronosyltransferase 1-4 P22310 UGT1A4 UDP-glucuronosyltransferase 1-6 P19224 UGT1A6 UDP-glucuronosyltransferase 1-9 O60656 UGT1A9 UDP-glucuronosyltransferase 2B4 P06133 UGT2B4 UDP-glucuronosyltransferase 2B7 P16662 UGT2B7