1.0 2011-09-21 01:50:12 UTC 2015-07-21 06:59:38 UTC FDB029107 10-HETE 10-HETE is a HETE(Hydroxyeicosatetraenoic acid)with the hydroxy group located in C-10 position. The HETE metabolites are identified as omega-hydroxy derivatives and 10-HETE is one of the major products of NADPH-dependent arachidonic acid metabolism in rat liver microsomes. The conversion of arachidonic acid to HETE can be catalyzed via lipoxygenase ,cyclooxygenase or P-450 dependent route. [PMID: 7646075] [HMDB] 10-hydroxyeicosa-all-cis-5,8,11,14-tetraenoate 10-hydroxyeicosa-all-cis-5,8,11,14-tetraenoic acid C20H32O3 320.4663 320.23514489 (5Z,8Z,11Z,14Z)-10-hydroxyicosa-5,8,11,14-tetraenoic acid (5Z,8Z,11Z,14Z)-10-hydroxyicosa-5,8,11,14-tetraenoic acid 167697-52-1 CCCCC\C=C/C\C=C/C(O)\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H32O3/c1-2-3-4-5-6-7-10-13-16-19(21)17-14-11-8-9-12-15-18-20(22)23/h6-9,13-14,16-17,19,21H,2-5,10-12,15,18H2,1H3,(H,22,23)/b7-6-,9-8-,16-13-,17-14- ZUOCVLADVGGUGH-OVMCANAPSA-N belongs to the class of organic compounds known as hydroxyeicosatetraenoic acids. These are eicosanoic acids with an attached hydroxyl group and four CC double bonds. Hydroxyeicosatetraenoic acids Organic compounds Lipids and lipid-like molecules Fatty Acyls Eicosanoids Aliphatic acyclic compounds Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Hydroxy fatty acids Long-chain fatty acids Monocarboxylic acids and derivatives Organic oxides Secondary alcohols Unsaturated fatty acids Alcohol Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Fatty acid Hydrocarbon derivative Hydroxy fatty acid Hydroxyeicosatetraenoic acid Long-chain fatty acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Secondary alcohol Unsaturated fatty acid Solid logp 5.84 ALOGPS logs -5.29 ALOGPS solubility 1.64e-03 g/l ALOGPS logp 5.51 ChemAxon pka_strongest_acidic 4.82 ChemAxon pka_strongest_basic -1.9 ChemAxon iupac (5Z,8Z,11Z,14Z)-10-hydroxyicosa-5,8,11,14-tetraenoic acid ChemAxon average_mass 320.4663 ChemAxon mono_mass 320.23514489 ChemAxon smiles CCCCC\C=C/C\C=C/C(O)\C=C/C\C=C/CCCC(O)=O ChemAxon formula C20H32O3 ChemAxon inchi InChI=1S/C20H32O3/c1-2-3-4-5-6-7-10-13-16-19(21)17-14-11-8-9-12-15-18-20(22)23/h6-9,13-14,16-17,19,21H,2-5,10-12,15,18H2,1H3,(H,22,23)/b7-6-,9-8-,16-13-,17-14- ChemAxon inchikey ZUOCVLADVGGUGH-OVMCANAPSA-N ChemAxon polar_surface_area 57.53 ChemAxon refractivity 101.32 ChemAxon polarizability 37.98 ChemAxon rotatable_bond_count 14 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 312067 Specdb::MsMs 312068 Specdb::MsMs 312069 Specdb::MsMs 357214 Specdb::MsMs 357215 Specdb::MsMs 357216 Specdb::MsMs 2732349 Specdb::MsMs 2732350 Specdb::MsMs 2732351 Specdb::MsMs 2976659 Specdb::MsMs 2976660 Specdb::MsMs 2976661 Specdb::CMs 20685 Specdb::CMs 39940 Specdb::CMs 147010 HMDB12508 #<Reference:0x000055ce32673288>