1.0 2011-09-21 01:50:19 UTC 2015-07-21 06:59:38 UTC FDB029113 11beta-Hydroxytestosterone 11beta-Hydroxytestosterone is a Testosterone derivative metabolite. Testosterone is reported to have an acute vasodilating action in vitro, an effect that may impart a favourable haemodynamic response in patients with chronic heart failure. [HMDB] 11beta,17beta-dihydroxyandrost-4-en-3-one C19H28O3 304.4238 304.203844762 (2R,14S,15S,17S)-14,17-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-5-one (2R,14S,15S,17S)-14,17-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-5-one 1816-85-9 C[C@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C1CC[C@@H]2O InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-17,21-22H,3-8,10H2,1-2H3/t13?,14?,15-,16-,17?,18-,19-/m0/s1 YQDZGFAYWGWSJK-UALLODJUSA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Androgens and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Aliphatic homopolycyclic compounds 11-beta-hydroxysteroids 17-hydroxysteroids 3-oxo delta-4-steroids Cyclic alcohols and derivatives Cyclohexenones Delta-4-steroids Hydrocarbon derivatives Organic oxides Secondary alcohols 11-beta-hydroxysteroid 11-hydroxysteroid 17-hydroxysteroid 3-oxo-delta-4-steroid 3-oxosteroid Alcohol Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic alcohol Cyclic ketone Cyclohexenone Delta-4-steroid Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Secondary alcohol Solid logp 1.81 ALOGPS logs -3.53 ALOGPS solubility 9.05e-02 g/l ALOGPS logp 2.06 ChemAxon pka_strongest_acidic 14.48 ChemAxon pka_strongest_basic -2.8 ChemAxon iupac (2R,14S,15S,17S)-14,17-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-5-one ChemAxon average_mass 304.4238 ChemAxon mono_mass 304.203844762 ChemAxon smiles C[C@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C1CC[C@@H]2O ChemAxon formula C19H28O3 ChemAxon inchi InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-17,21-22H,3-8,10H2,1-2H3/t13?,14?,15-,16-,17?,18-,19-/m0/s1 ChemAxon inchikey YQDZGFAYWGWSJK-UALLODJUSA-N ChemAxon polar_surface_area 57.53 ChemAxon refractivity 86.02 ChemAxon polarizability 34.81 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 20177 Specdb::CMs 39946 Specdb::CMs 133822 Specdb::CMs 141556 Specdb::MsMs 310951 Specdb::MsMs 310952 Specdb::MsMs 310953 Specdb::MsMs 355822 Specdb::MsMs 355823 Specdb::MsMs 355824 Specdb::MsMs 2419692 Specdb::MsMs 2419693 Specdb::MsMs 2419694 Specdb::MsMs 2543378 Specdb::MsMs 2543379 Specdb::MsMs 2543380 HMDB12533