1.0 2011-09-21 01:52:45 UTC 2015-07-21 06:59:40 UTC FDB029258 omega-Carboxy-trinor-leukotriene B4 omega-Carboxy-trinor-leukotriene B4 belongs to the leukotriene family Leukotrienes are eicosanoids. The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs), leukotrienes (LTs) and lipoxins (LXs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes) and leukotrienes from leukocytes, hence the derivation of their names. All mammalian cells except erythrocytes synthesize eicosanoids. These molecules are extremely potent, able to cause profound physiological effects at very dilute concentrations. All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signaling pathways. [HMDB] 7R,14S-dihydroxy-1,18-octadec-4,12Z,8,10E-tetraendioate 7R,14S-dihydroxy-1,18-octadec-4,12Z,8,10E-tetraendioic acid 7R,14S-dihydroxy-1,18-octadec-4,12Z,8,10E-tetraendioic acid anion omega-COOH-dinor-LTB(,4) C18H26O6 338.3954 338.172938564 (4Z,7S,8E,10E,12Z,14R)-7,14-dihydroxyoctadeca-4,8,10,12-tetraenedioic acid (4Z,7S,8E,10E,12Z,14R)-7,14-dihydroxyoctadeca-4,8,10,12-tetraenedioic acid O[C@H](CCCC(O)=O)\C=C/C=C/C=C/[C@@H](O)C\C=C/CCC(O)=O InChI=1S/C18H26O6/c19-15(11-6-3-7-13-17(21)22)9-4-1-2-5-10-16(20)12-8-14-18(23)24/h1-6,9-10,15-16,19-20H,7-8,11-14H2,(H,21,22)(H,23,24)/b2-1+,6-3-,9-4+,10-5-/t15-,16+/m1/s1 XWRIIHRGMKHPHN-LLVPEOCGSA-N belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. Long-chain fatty acids Organic compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates Aliphatic acyclic compounds Carbonyl compounds Carboxylic acids Dicarboxylic acids and derivatives Hydrocarbon derivatives Hydroxy fatty acids Organic oxides Secondary alcohols Unsaturated fatty acids Alcohol Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Dicarboxylic acid or derivatives Hydrocarbon derivative Hydroxy fatty acid Long-chain fatty acid Organic oxide Organic oxygen compound Organooxygen compound Secondary alcohol Unsaturated fatty acid Solid logp 2.30 ALOGPS logs -3.58 ALOGPS solubility 8.82e-02 g/l ALOGPS logp 1.92 ChemAxon pka_strongest_acidic 4.34 ChemAxon pka_strongest_basic -1.3 ChemAxon iupac (4Z,7S,8E,10E,12Z,14R)-7,14-dihydroxyoctadeca-4,8,10,12-tetraenedioic acid ChemAxon average_mass 338.3954 ChemAxon mono_mass 338.172938564 ChemAxon smiles O[C@H](CCCC(O)=O)\C=C/C=C/C=C/[C@@H](O)C\C=C/CCC(O)=O ChemAxon formula C18H26O6 ChemAxon inchi InChI=1S/C18H26O6/c19-15(11-6-3-7-13-17(21)22)9-4-1-2-5-10-16(20)12-8-14-18(23)24/h1-6,9-10,15-16,19-20H,7-8,11-14H2,(H,21,22)(H,23,24)/b2-1+,6-3-,9-4+,10-5-/t15-,16+/m1/s1 ChemAxon inchikey XWRIIHRGMKHPHN-LLVPEOCGSA-N ChemAxon polar_surface_area 115.06 ChemAxon refractivity 95.45 ChemAxon polarizability 36.63 ChemAxon rotatable_bond_count 13 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 26050 Specdb::CMs 40038 Specdb::CMs 134624 Specdb::CMs 142358 Specdb::MsMs 323716 Specdb::MsMs 323717 Specdb::MsMs 323718 Specdb::MsMs 371944 Specdb::MsMs 371945 Specdb::MsMs 371946 Specdb::MsMs 3047487 Specdb::MsMs 3047488 Specdb::MsMs 3047489 Specdb::MsMs 3095587 Specdb::MsMs 3095588 Specdb::MsMs 3095589 HMDB13032