Record Information
Version1.0
Creation date2015-05-07 20:39:26 UTC
Update date2020-09-17 15:40:29 UTC
Primary IDFDB030969
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameL-ornithine
DescriptionOrnithine, also known as (S)-ornithine, belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. Ornithine is a drug which is used for nutritional supplementation, also for treating dietary shortage or imbalance. it has been claimed that ornithine improves athletic performance, has anabolic effects, has wound-healing effects, and is immuno-enhancing. Ornithine is a very strong basic compound (based on its pKa). Ornithine exists in all living species, ranging from bacteria to humans. Within humans, ornithine participates in a number of enzymatic reactions. In particular, carbamoyl phosphate and ornithine can be converted into citrulline; which is mediated by the enzyme ornithine carbamoyltransferase, mitochondrial. In addition, ornithine and urea can be biosynthesized from L-arginine; which is mediated by the enzyme arginase-1. In humans, ornithine is involved in the metabolic disorder called argininemia. Outside of the human body, Ornithine has been detected, but not quantified in, several different foods, such as lemon thymes, black elderberries, tronchuda cabbages, black mulberries, and bilberries. This could make ornithine a potential biomarker for the consumption of these foods. Ornithine is a potentially toxic compound. Ornithine, with regard to humans, has been found to be associated with several diseases such as ulcerative colitis, myopathy, lactic acidosis, and sideroblastic anemia 1, and perillyl alcohol administration for cancer treatment; ornithine has also been linked to several inborn metabolic disorders including hyperdibasic aminoaciduria I and ornithine transcarbamylase deficiency. An optically active form of ornithine having L-configuration.
CAS Number70-26-8
Structure
Thumb
Synonyms
SynonymSource
Predicted PropertiesNot Available
Chemical FormulaC5H12N2O2
IUPAC name
InChI IdentifierInChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
InChI KeyAHLPHDHHMVZTML-BYPYZUCNSA-N
Isomeric SMILESNCCC[C@H](N)C(O)=O
Average Molecular Weight132.161
Monoisotopic Molecular Weight132.089877638
Classification
ClassificationNot classified
Ontology
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Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
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Refractive IndexNot Available
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ChemSpider IDNot Available
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KEGG Compound IDNot Available
Pubchem Compound IDNot Available
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ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDNot Available
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
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KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
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Health Effects / BioactivitiesNot Available
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General ReferenceNot Available
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