1.0 2026-09-22 09:14:56 UTC 2026-09-22 09:14:56 UTC FDB118028 Andrographin 5-hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)chromen-4-one C18H16O6 328.32 328.094688235 5-hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)-4H-chromen-4-one andrographin COC1=CC(O)=C2C(=O)C=C(OC2=C1OC)C1=CC=CC=C1OC InChI=1S/C18H16O6/c1-21-13-7-5-4-6-10(13)14-8-11(19)16-12(20)9-15(22-2)17(23-3)18(16)24-14/h4-9,20H,1-3H3 AJMNTEFGXPRZHG-UHFFFAOYSA-N belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. 8-O-methylated flavonoids Organic compounds Phenylpropanoids and polyketides Flavonoids O-methylated flavonoids Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 2'-O-methylated flavonoids 5-hydroxyflavonoids 7-O-methylated flavonoids Alkyl aryl ethers Anisoles Chromones Flavones Heteroaromatic compounds Hydrocarbon derivatives Methoxybenzenes Organic oxides Oxacyclic compounds Phenoxy compounds Pyranones and derivatives Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 2p-methoxyflavonoid-skeleton 5-hydroxyflavonoid 7-methoxyflavonoid-skeleton 8-methoxyflavonoid-skeleton Alkyl aryl ether Anisole Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Ether Flavone Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid Methoxybenzene Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Phenol ether Phenoxy compound Pyran Pyranone Vinylogous acid Flavones and Flavonols logp 3.35 ALOGPS logs -4.12 ALOGPS solubility 2.47e-02 g/l ALOGPS logp 2.84 ChemAxon pka_strongest_acidic 7.88 ChemAxon pka_strongest_basic -4.4 ChemAxon iupac 5-hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)-4H-chromen-4-one ChemAxon average_mass 328.32 ChemAxon mono_mass 328.094688235 ChemAxon smiles COC1=CC(O)=C2C(=O)C=C(OC2=C1OC)C1=CC=CC=C1OC ChemAxon formula C18H16O6 ChemAxon inchi InChI=1S/C18H16O6/c1-21-13-7-5-4-6-10(13)14-8-11(19)16-12(20)9-15(22-2)17(23-3)18(16)24-14/h4-9,20H,1-3H3 ChemAxon inchikey AJMNTEFGXPRZHG-UHFFFAOYSA-N ChemAxon polar_surface_area 74.22 ChemAxon refractivity 88.34 ChemAxon polarizability 33.21 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 6 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon