1.0 2026-09-22 23:30:26 UTC 2026-09-22 23:30:26 UTC FDB119084 Difloxacin 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid C21H19F2N3O3 399.398 399.13944781 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid difloxacin CN1CCN(CC1)C1=C(F)C=C2C(=C1)N(C=C(C(O)=O)C2=O)C1=CC=C(F)C=C1 InChI=1S/C21H19F2N3O3/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14/h2-5,10-12H,6-9H2,1H3,(H,28,29) NOCJXYPHIIZEHN-UHFFFAOYSA-N belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group. Phenylquinolines Organic compounds Organoheterocyclic compounds Quinolines and derivatives Phenylquinolines Aromatic heteropolycyclic compounds Amino acids Aminoquinolines and derivatives Aryl fluorides Azacyclic compounds Carboxylic acids Dialkylarylamines Fluorobenzenes Fluoroquinolones Haloquinolines Heteroaromatic compounds Hydrocarbon derivatives Hydroquinolines Hydroquinolones Monocarboxylic acids and derivatives N-arylpiperazines N-methylpiperazines Organic oxides Organofluorides Organooxygen compounds Organopnictogen compounds Pyridinecarboxylic acids Quinoline carboxylic acids Trialkylamines Vinylogous amides 1,4-diazinane Amine Amino acid Amino acid or derivatives Aminoquinoline Aromatic heteropolycyclic compound Aryl fluoride Aryl halide Azacycle Benzenoid Carboxylic acid Carboxylic acid derivative Dialkylarylamine Dihydroquinoline Dihydroquinolone Fluorobenzene Fluoroquinolone Halobenzene Haloquinoline Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Monocyclic benzene moiety N-alkylpiperazine N-arylpiperazine N-methylpiperazine Organic nitrogen compound Organic oxide Organic oxygen compound Organofluoride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenylquinoline Piperazine Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Quinoline-3-carboxylic acid Tertiary aliphatic amine Tertiary aliphatic/aromatic amine Tertiary amine Vinylogous amide quinolines logp 1.16 ALOGPS logs -3.50 ALOGPS solubility 1.26e-01 g/l ALOGPS logp 2.36 ChemAxon pka_strongest_acidic 5.64 ChemAxon pka_strongest_basic 6.45 ChemAxon iupac 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ChemAxon average_mass 399.398 ChemAxon mono_mass 399.13944781 ChemAxon smiles CN1CCN(CC1)C1=C(F)C=C2C(=C1)N(C=C(C(O)=O)C2=O)C1=CC=C(F)C=C1 ChemAxon formula C21H19F2N3O3 ChemAxon inchi InChI=1S/C21H19F2N3O3/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14/h2-5,10-12H,6-9H2,1H3,(H,28,29) ChemAxon inchikey NOCJXYPHIIZEHN-UHFFFAOYSA-N ChemAxon polar_surface_area 64.09 ChemAxon refractivity 105.19 ChemAxon polarizability 39.25 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 6 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 104379 Specdb::CMs 116358 Specdb::CMs 873054 Specdb::CMs 873055 Specdb::MsMs 246615 Specdb::MsMs 246616 Specdb::MsMs 246617 Specdb::MsMs 266559 Specdb::MsMs 266560 Specdb::MsMs 266561 Specdb::MsMs 440761 Specdb::MsMs 440762 Specdb::MsMs 440763 Specdb::MsMs 440764 Specdb::MsMs 440765 Specdb::MsMs 440766 Specdb::MsMs 444626 Specdb::MsMs 444627 Specdb::MsMs 444628 Specdb::MsMs 444629 Specdb::MsMs 444630 Specdb::MsMs 444631 Specdb::MsMs 444632 Specdb::MsMs 444633 Specdb::MsMs 444634 Specdb::MsMs 2236316 Specdb::MsMs 2238144 Specdb::MsMs 2238485 Specdb::MsMs 2239114