1.02010-04-08 22:08:43 UTC2018-05-28 18:59:22 UTCFDB009612Hydroxypropyl celluloseHydroxypropyl cellulose (cellulose, 2-hydroxypropyl ether) is a derivative of cellulose with both water solubility and organic solubility. Hydroxypropyl cellulose acts to stabilize and thicken the precorneal tear film and prolong the tear film breakup time which is usually accelerated in patients with dry eye states. Hydroxypropyl cellulose also acts to lubricate and protect the eye. Hydroxypropyl cellulose usually reduces the signs and symptoms resulting from moderate to severe dry eye syndromes, such as conjunctival hyperemia, corneal and conjunctival staining with rose bengal, exudation, itching, burning, foreign body sensation, smarting, photophobia, dryness and blurred or cloudy vision. Progressive visual deterioration which occurs in some patients may be retarded, halted, or sometimes reversed.3-Hydroxy-2-phenyl-4-quinolinecarboxylic acid3-Hydroxy-2-phenyl-cinchoninic acid3-Hydroxy-2-phenylcinchoninic acid3-hydroxy-2-phenylquinoline-4-carboxylic acid3-Hydroxycinchophen4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl-4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl- (9CI)ChinoxoneCinchoninic acid, 3-hydroxy-2-phenyl-FenidroneHPCHPC (van)HydroxycinchopheneLacrisertMagnofenylMagnophenylOxicinchophenumOxicincofenoOxinofenOxycinchophenOxycinchophen (inn)Oxycinchophen [inn:ban]OxycinchopheneOxycinchophenumReumartrilSintofeneC16H11NO3265.2634265.0738932233-hydroxy-2-phenylquinoline-4-carboxylic acidoxycinchophen9004-64-2OC(=O)C1=C(O)C(=NC2=CC=CC=C12)C1=CC=CC=C1InChI=1S/C16H11NO3/c18-15-13(16(19)20)11-8-4-5-9-12(11)17-14(15)10-6-2-1-3-7-10/h1-9,18H,(H,19,20)XAPRFLSJBSXESP-UHFFFAOYSA-N belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group.PhenylquinolinesOrganic compoundsOrganoheterocyclic compoundsQuinolines and derivativesPhenylquinolinesAromatic heteropolycyclic compoundsAzacyclic compoundsBenzene and substituted derivativesCarboxylic acidsHeteroaromatic compoundsHydrocarbon derivativesHydroxypyridinesHydroxyquinolinesMonocarboxylic acids and derivativesOrganic oxidesOrganonitrogen compoundsOrganooxygen compoundsOrganopnictogen compoundsPhenylpyridinesPyridinecarboxylic acidsQuinoline carboxylic acidsVinylogous acids2-phenylpyridineAromatic heteropolycyclic compoundAzacycleBenzenoidCarboxylic acidCarboxylic acid derivativeHeteroaromatic compoundHydrocarbon derivativeHydroxypyridineHydroxyquinolineMonocarboxylic acid or derivativesMonocyclic benzene moietyOrganic nitrogen compoundOrganic oxideOrganic oxygen compoundOrganonitrogen compoundOrganooxygen compoundOrganopnictogen compoundPhenylquinolinePyridinePyridine carboxylic acidPyridine carboxylic acid or derivativesQuinoline-4-carboxylic acidVinylogous acidlogp3.86logs-3.49solubility8.49e-02 g/llogp3.94pka_strongest_acidic3.36pka_strongest_basic1.72iupac3-hydroxy-2-phenylquinoline-4-carboxylic acidaverage_mass265.2634mono_mass265.073893223smilesOC(=O)C1=C(O)C(=NC2=CC=CC=C12)C1=CC=CC=C1formulaC16H11NO3inchiInChI=1S/C16H11NO3/c18-15-13(16(19)20)11-8-4-5-9-12(11)17-14(15)10-6-2-1-3-7-10/h1-9,18H,(H,19,20)inchikeyXAPRFLSJBSXESP-UHFFFAOYSA-Npolar_surface_area70.42refractivity73.98polarizability27.36rotatable_bond_count2acceptor_count4donor_count2physiological_charge-1formal_charge0Specdb::CMs15224Specdb::CMs42813Specdb::MsMs71013Specdb::MsMs71014Specdb::MsMs71015Specdb::MsMs129594Specdb::MsMs129595Specdb::MsMs129596HMDB32337#<Reference:0x00005556740acd80>#<Reference:0x00005556740acbc8>#<Reference:0x00005556740ac970>#<Reference:0x00005556740ac7b8>odorless