1.0 2011-09-21 00:09:18 UTC 2025-11-19 02:40:59 UTC FDB022156 Succinylacetone Succinylacetone is a tyrosine metabolite (PMID 16448836). It is a specific marker for Tyrosinemia type I. Type I tyrosinemia is an inherited metabolism disorder due to a shortage of the enzyme fumarylacetoacetate hydrolase that is needed to break down tyrosine. [HMDB] 4,6-Dioxoheptanoate 4,6-Dioxoheptanoic acid 6-Dioxoheptanoate Succinylacetone C7H10O4 158.1519 158.057908808 4,6-dioxoheptanoic acid succinylacetone 51568-18-4 CC(=O)CC(=O)CCC(O)=O InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11) WYEPBHZLDUPIOD-UHFFFAOYSA-N belongs to the class of organic compounds known as medium-chain keto acids and derivatives. These are keto acids with a 6 to 12 carbon atoms long side chain. Medium-chain keto acids and derivatives Organic compounds Organic acids and derivatives Keto acids and derivatives Medium-chain keto acids and derivatives Aliphatic acyclic compounds Beta-diketones Carboxylic acids Gamma-keto acids and derivatives Hydrocarbon derivatives Ketones Monocarboxylic acids and derivatives Organic oxides 1,3-dicarbonyl compound 1,3-diketone Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Gamma-keto acid Hydrocarbon derivative Ketone Medium-chain keto acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Solid logp -0.18 ALOGPS logs -0.82 ALOGPS solubility 2.41e+01 g/l ALOGPS logp 0.15 ChemAxon pka_strongest_acidic 4.15 ChemAxon pka_strongest_basic -7.2 ChemAxon iupac 4,6-dioxoheptanoic acid ChemAxon average_mass 158.1519 ChemAxon mono_mass 158.057908808 ChemAxon smiles CC(=O)CC(=O)CCC(O)=O ChemAxon formula C7H10O4 ChemAxon inchi InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11) ChemAxon inchikey WYEPBHZLDUPIOD-UHFFFAOYSA-N ChemAxon polar_surface_area 71.44 ChemAxon refractivity 36.98 ChemAxon polarizability 15.07 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::MsIr 694 Specdb::MsIr 695 Specdb::MsIr 696 Specdb::NmrTwoD 1393 Specdb::CMs 17977 Specdb::CMs 37664 Specdb::CMs 153758 Specdb::CMs 1070812 Specdb::CMs 1070813 Specdb::CMs 1070815 Specdb::CMs 1070817 Specdb::CMs 1070819 Specdb::CMs 1070821 Specdb::CMs 1070822 Specdb::CMs 1070824 Specdb::CMs 1070826 Specdb::EiMs 564 Specdb::MsMs 867 Specdb::MsMs 868 Specdb::MsMs 869 Specdb::MsMs 10079 Specdb::MsMs 10080 Specdb::MsMs 10081 Specdb::MsMs 16751 Specdb::MsMs 16752 Specdb::MsMs 16753 Specdb::MsMs 2235786 Specdb::MsMs 2237610 Specdb::MsMs 2237916 Specdb::MsMs 2239640 Specdb::MsMs 2240074 Specdb::MsMs 2241655 Specdb::MsMs 2765825 Specdb::MsMs 2765826 Specdb::MsMs 2765827 Specdb::MsMs 2942944 Specdb::MsMs 2942945 Specdb::MsMs 2942946 Specdb::NmrOneD 1448 Specdb::NmrOneD 7262 Specdb::NmrOneD 7263 Specdb::NmrOneD 7264 Specdb::NmrOneD 7265 Specdb::NmrOneD 7266 Specdb::NmrOneD 7267 Specdb::NmrOneD 7268 Specdb::NmrOneD 7269 Specdb::NmrOneD 7270 Specdb::NmrOneD 7271 Specdb::NmrOneD 7272 Specdb::NmrOneD 7273 Specdb::NmrOneD 7274 Specdb::NmrOneD 7275 Specdb::NmrOneD 7276 Specdb::NmrOneD 7277 Specdb::NmrOneD 7278 Specdb::NmrOneD 7279 Specdb::NmrOneD 7280 Specdb::NmrOneD 7281 HMDB00635 SHU #<Reference:0x000055ce318463e0> #<Reference:0x000055ce31846200> #<Reference:0x000055ce31846048> #<Reference:0x000055ce31845e90> #<Reference:0x000055ce31845cd8> #<Reference:0x000055ce31845b20> #<Reference:0x000055ce31845940> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823