Record Information
Version1.0
Creation date2011-09-21 00:13:26 UTC
Update date2015-07-21 06:57:11 UTC
Primary IDFDB022400
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameIodate
DescriptionAn iodate is a salt of iodic acid. Because it is more stable than iodide, most health authorities preferentially recommend iodate as an additive to salt for correcting iodine deficiency. Even in a low exposure, doubts have been raised whether the safety of iodate. In humans and rats, oral bioavailability of iodine from iodate is virtually equivalent to that from iodide. When given intravenously to rats, or when added to whole blood or tissue homogenates in vitro or to foodstuff, iodate is quantitatively reduced to iodide by nonenzymatic reactions, and thus becomes available to the body as iodide. Therefore, except perhaps for the gastrointestinal mucosa, exposure of tissues to iodate might be minimal. At much higher doses given intravenously (i.e., above 10 mg/kg), iodate is highly toxic to the retina. Ocular toxicity in humans has occurred only after exposure to doses of 600 to 1,200 mg per individual. Oral exposures of several animal species to high doses, exceeding the human intake from fortified salt by orders of magnitude, pointed to corrosive effects in the gastrointestinal tract, hemolysis, nephrotoxicity, and hepatic injury. Genotoxicity and carcinogenicity data for iodate are scarce or nonexistent. (PMID: 11396703) [HMDB]
CAS Number15454-31-6
Structure
Thumb
Synonyms
Predicted Properties
PropertyValueSource
logP0.18ChemAxon
pKa (Strongest Acidic)0.85ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area57.2 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity17.67 m³·mol⁻¹ChemAxon
Polarizability7.85 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Chemical FormulaIO3
IUPAC nameiodate
InChI IdentifierInChI=1S/HIO3/c2-1(3)4/h(H,2,3,4)/p-1
InChI KeyICIWUVCWSCSTAQ-UHFFFAOYSA-M
Isomeric SMILES[O-][I](=O)=O
Average Molecular Weight174.9027
Monoisotopic Molecular Weight174.889212286
Classification
Description Belongs to the class of inorganic compounds known as non-metal iodates. These are inorganic non-metallic compounds containing a iodate as its largest oxoanion.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassNon-metal oxoanionic compounds
Sub ClassNon-metal iodates
Direct ParentNon-metal iodates
Alternative Parents
Substituents
  • Non-metal iodate
  • Inorganic oxide
Molecular FrameworkNot Available
External Descriptors
Ontology
OntologyNo ontology term
Physico-Chemical Properties
Physico-Chemical Properties - Experimental
Spectra
Spectra
EI-MS/GC-MSNot Available
MS/MS
TypeDescriptionSplash KeyView
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-00di-0900000000-ac756e98a6eb7491b4482017-09-01View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-00di-0900000000-ac756e98a6eb7491b4482017-09-01View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-00di-0900000000-ac756e98a6eb7491b4482017-09-01View Spectrum
NMRNot Available
ChemSpider ID76615
ChEMBL IDNot Available
KEGG Compound IDNot Available
Pubchem Compound ID84927
Pubchem Substance IDNot Available
ChEBI ID29226
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB01061
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDIodate
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
Processing...
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference