1.0 2011-09-21 00:34:13 UTC 2015-07-21 06:57:50 UTC FDB023754 Melanostatin Melanostatin (prolyl-leucyl-glycinamide) is a peptide hormone produced in the hypothalamus that inhibits the release of melanocyte-stimulating hormone (MSH). [HMDB] 7-9-Oxytocin L-proline-l-leucine-glycine-amide L-prolyl-l-leucylglycinamide L-prolyl-l-leucylglycylamide Melanostatin I (ox) MIF-I MSH-release inhibiting factor I Oxytocin c-terminal tripeptide Prolylleucylglycine amide C13H24N4O3 284.3547 284.184840654 (2S)-N-(carbamoylmethyl)-4-methyl-2-[(2S)-pyrrolidin-2-ylformamido]pentanamide L-prolyl-l-leucylglycinamide 9083-38-9 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds. Oligopeptides Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aliphatic heteromonocyclic compounds Alpha amino acid amides Azacyclic compounds Carbonyl compounds Dialkylamines Hydrocarbon derivatives Leucine and derivatives N-acyl amines N-acyl-alpha amino acids and derivatives Organic oxides Organopnictogen compounds Primary carboxylic acid amides Proline and derivatives Pyrrolidinecarboxamides Secondary carboxylic acid amides Aliphatic heteromonocyclic compound Alpha-amino acid amide Alpha-amino acid or derivatives Alpha-oligopeptide Amine Amino acid or derivatives Azacycle Carbonyl group Carboxamide group Fatty acyl Fatty amide Hydrocarbon derivative Leucine or derivatives N-acyl-alpha amino acid or derivatives N-acyl-amine N-substituted-alpha-amino acid Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary carboxylic acid amide Proline or derivatives Pyrrolidine Pyrrolidine carboxylic acid or derivatives Pyrrolidine-2-carboxamide Secondary aliphatic amine Secondary amine Secondary carboxylic acid amide Solid logp -0.82 ALOGPS logs -2.82 ALOGPS solubility 4.26e-01 g/l ALOGPS logp -1.3 ChemAxon pka_strongest_acidic 12.46 ChemAxon pka_strongest_basic 9.5 ChemAxon iupac (2S)-N-(carbamoylmethyl)-4-methyl-2-[(2S)-pyrrolidin-2-ylformamido]pentanamide ChemAxon average_mass 284.3547 ChemAxon mono_mass 284.184840654 ChemAxon smiles CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O ChemAxon formula C13H24N4O3 ChemAxon inchi InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 ChemAxon inchikey NOOJLZTTWSNHOX-UWVGGRQHSA-N ChemAxon polar_surface_area 113.32 ChemAxon refractivity 73.66 ChemAxon polarizability 30.58 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 4 ChemAxon donor_count 4 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 26573 Specdb::CMs 133326 Specdb::CMs 141060 Specdb::NmrOneD 54982 Specdb::NmrOneD 54983 Specdb::NmrOneD 54984 Specdb::NmrOneD 54985 Specdb::NmrOneD 54986 Specdb::NmrOneD 54987 Specdb::NmrOneD 54988 Specdb::NmrOneD 54989 Specdb::NmrOneD 54990 Specdb::NmrOneD 54991 Specdb::NmrOneD 54992 Specdb::NmrOneD 54993 Specdb::NmrOneD 54994 Specdb::NmrOneD 54995 Specdb::NmrOneD 54996 Specdb::NmrOneD 54997 Specdb::NmrOneD 54998 Specdb::NmrOneD 54999 Specdb::NmrOneD 55000 Specdb::NmrOneD 55001 Specdb::MsMs 324919 Specdb::MsMs 324920 Specdb::MsMs 324921 Specdb::MsMs 373459 Specdb::MsMs 373460 Specdb::MsMs 373461 Specdb::MsMs 3044875 Specdb::MsMs 3044876 Specdb::MsMs 3044877 Specdb::MsMs 3099349 Specdb::MsMs 3099350 Specdb::MsMs 3099351 HMDB05764 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823