1.0 2010-04-08 22:06:39 UTC 2025-11-18 22:58:57 UTC FDB005347 Germacrone Germacrone is a member of the class of compounds known as germacrane sesquiterpenoids. Germacrane sesquiterpenoids are sesquiterpenoids having the germacrane skeleton, with a structure characterized by a cyclodecane ring substituted with an isopropyl and two methyl groups. Germacrone is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Germacrone can be found in common thyme and turmeric, which makes germacrone a potential biomarker for the consumption of these food products. Germacrone is an antiviral isolate of Geranium macrorrhizum . (e,e)-germacrone Germacra-3,7(11),9-trien-6-one, (E,E)- Germacron Germacrone C15H22O 218.3346 218.167065326 (3E,7E)-3,7-dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one (3E,7E)-3,7-dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one 6902-91-6 CC(C)=C1C\C=C(C)\CC\C=C(C)\CC1=O InChI=1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+ CAULGCQHVOVVRN-SWZPTJTJSA-N belongs to the class of organic compounds known as germacrane sesquiterpenoids. These are sesquiterpenoids having the germacrane skeleton, with a structure characterized by a cyclodecane ring substituted with an isopropyl and two methyl groups. Germacrane sesquiterpenoids Organic compounds Lipids and lipid-like molecules Prenol lipids Sesquiterpenoids Aliphatic homomonocyclic compounds Cyclic ketones Hydrocarbon derivatives Organic oxides Aliphatic homomonocyclic compound Carbonyl group Cyclic ketone Germacrane sesquiterpenoid Hydrocarbon derivative Ketone Organic oxide Organic oxygen compound Organooxygen compound logp 4.61 ALOGPS logs -3.24 ALOGPS solubility 1.26e-01 g/l ALOGPS logp 4.11 ChemAxon pka_strongest_acidic 16.77 ChemAxon pka_strongest_basic -4.7 ChemAxon iupac (3E,7E)-3,7-dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one ChemAxon average_mass 218.3346 ChemAxon mono_mass 218.167065326 ChemAxon smiles CC(C)=C1C\C=C(C)\CC\C=C(C)\CC1=O ChemAxon formula C15H22O ChemAxon inchi InChI=1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+ ChemAxon inchikey CAULGCQHVOVVRN-SWZPTJTJSA-N ChemAxon polar_surface_area 17.07 ChemAxon refractivity 71.78 ChemAxon polarizability 25.79 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 1 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 74445 Specdb::MsMs 74446 Specdb::MsMs 74447 Specdb::MsMs 133830 Specdb::MsMs 133831 Specdb::MsMs 133832 Common thyme Type 1 specific Thymus vulgaris 49992 Turmeric Type 1 specific Curcuma longa 136217 Analgesic 56 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Anti ulcer 676 One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. Anti-edemic 248 Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-stress 632 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-tussive 674 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Hypothermic 1023