| Record Information |
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| Version | 1.0 |
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| Creation date | 2010-04-08 22:11:22 UTC |
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| Update date | 2019-11-26 03:10:27 UTC |
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| Primary ID | FDB014613 |
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| Secondary Accession Numbers | |
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| Chemical Information |
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| FooDB Name | beta-Carotene |
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| Description | beta-Carotene, also known as b-karotin or β-carotene, belongs to the class of organic compounds known as carotenes. These are a type of unsaturated hydrocarbons containing eight consecutive isoprene units. They are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Thus, beta-carotene is considered to be an isoprenoid. Based on a literature review a significant number of articles have been published on beta-Carotene. |
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| CAS Number | 7235-40-7 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| 1,1'-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-Tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl]bis(2,6,6-trimethylcyclohexene) | ChEBI | | all-trans-beta-Carotene | ChEBI | | beta-Karotin | ChEBI | | all-trans-b-Carotene | Generator | | all-trans-Β-carotene | Generator | | b-Karotin | Generator | | Β-karotin | Generator | | b-Carotene | Generator | | Β-carotene | Generator | | (all-e)-1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis | HMDB | | (all-e)-1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis[2,6,6-trimethyl-cyclohexene | HMDB | | all-e-b-Carotene | HMDB | | all-epsilon-beta-Carotene | HMDB | | Betacarotene | HMDB | | BetaVit | HMDB | | Carotaben | HMDB | | Carotene base 80S | HMDB | | FOOD Orange 5 | HMDB | | KPMK | HMDB | | Lucaratin | HMDB | | Lucarotin | HMDB | | Lurotin | HMDB | | Provatene | HMDB | | Provatenol | HMDB | | Rovimix b-carotene | HMDB | | Serlabo | HMDB | | Solatene | HMDB | | Hermal brand OF betacarotene | HMDB | | Max-caro | HMDB | | Merck brand OF betacarotene | HMDB | | Roche brand OF betacarotene | HMDB | | BellaCarotin | HMDB | | Betacarotene roche brand | HMDB | | Betacarotene solgar brand | HMDB | | Marlyn brand OF betacarotene | HMDB | | Betacarotene hermal brand | HMDB | | Max caro | HMDB | | Solgar brand OF betacarotene | HMDB | | 3m Brand OF betacarotene | HMDB | | Betacarotene 3m brand | HMDB | | Betacarotene marlyn brand | HMDB | | Betacarotene merck brand | HMDB | | Carotene, beta | HMDB | | MaxCaro | HMDB | | Vetoron | HMDB | | beta Carotene | HMDB | | b Carotene | HMDB | | Β carotene | HMDB | | beta-Carotene | HMDB | | β-Carotene | biospider | | β,β-Carotene | biospider | | 1,1'-[(1e,3e,5e,7e,9e,11e,13e,15e,17e)-3,7,12,16-Tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl]bis(2,6,6-trimethylcyclohexene) | ChEBI | | all-trans-β-carotene | Generator | | b,b-Carotene | db_source | | Betacarotene, INN, USAN | db_source | | C.I. Food Orange 5 | biospider | | E160a | db_source | | Food Orange 5 | biospider | | Phenoro | db_source | | trans-b-carotene | biospider | | β-carotene | Generator | | β-karotin | Generator |
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| Predicted Properties | |
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| Chemical Formula | C40H56 |
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| IUPAC name | 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-1-ene |
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| InChI Identifier | InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+ |
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| InChI Key | OENHQHLEOONYIE-JLTXGRSLSA-N |
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| Isomeric SMILES | C\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C |
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| Average Molecular Weight | 536.888 |
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| Monoisotopic Molecular Weight | 536.438201803 |
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| Classification |
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| Description | Belongs to the class of organic compounds known as carotenes. These are a type of unsaturated hydrocarbons containing eight consecutive isoprene units. They are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. |
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| Kingdom | Organic compounds |
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| Super Class | Lipids and lipid-like molecules |
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| Class | Prenol lipids |
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| Sub Class | Tetraterpenoids |
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| Direct Parent | Carotenes |
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| Alternative Parents | |
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| Substituents | - Carotene
- Branched unsaturated hydrocarbon
- Cycloalkene
- Cyclic olefin
- Unsaturated aliphatic hydrocarbon
- Unsaturated hydrocarbon
- Olefin
- Hydrocarbon
- Aliphatic homomonocyclic compound
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| Molecular Framework | Aliphatic homomonocyclic compounds |
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| External Descriptors | |
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| Ontology |
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| Ontology | No ontology term |
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| Physico-Chemical Properties |
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| Physico-Chemical Properties - Experimental | | Property | Value | Reference |
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| Physical state | Solid | |
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| Physical Description | Not Available | |
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| Mass Composition | C 89.49%; H 10.51% | DFC |
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| Melting Point | Mp 183° (sealed tube) | DFC |
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| Boiling Point | Not Available | |
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| Experimental Water Solubility | 0.0006 mg/mL | GREEN,FJ (1991) |
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| Experimental logP | Not Available | |
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| Experimental pKa | Not Available | |
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| Isoelectric point | Not Available | |
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| Charge | Not Available | |
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| Optical Rotation | Not Available | |
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| Spectroscopic UV Data | 520 () (CS2) | DFC |
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| Density | Not Available | |
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| Refractive Index | Not Available | |
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| Spectra |
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| Spectra | |
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| EI-MS/GC-MS | | Type | Description | Splash Key | View |
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| EI-MS | Mass Spectrum (Electron Ionization) | splash10-05mx-9810010000-9a261fb8602890c2481e | 2015-03-01 | View Spectrum | | Predicted GC-MS | Carotene, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-00di-3211290000-f968c686d39ae0f0fc50 | Spectrum |
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| MS/MS | | Type | Description | Splash Key | View |
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| MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated) | splash10-0016-2794670000-c5bc2a4dbcd0f12cbf7f | 2012-07-24 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated) | splash10-0002-2687970000-782d048d873c21fc6b82 | 2012-07-24 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated) | splash10-05ai-1009510000-585581456b10671692bd | 2012-07-24 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - FAB-EBEB (JMS-HX/HX 110A, JEOL) , Positive | splash10-05mx-2920010000-471219f3e66bafb29bee | 2012-08-31 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - , positive | splash10-0006-0144900000-2fa7b609c7300ff8aba3 | 2017-09-14 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-000i-0434190000-0f2f0f2c4af76e6c3322 | 2016-09-12 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-000b-0679100000-6f4450c8ade1963f9201 | 2016-09-12 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-000j-1789100000-6f2a7024e42303e7737a | 2016-09-12 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-000i-0000090000-cdea7c2d939f0c68b905 | 2016-09-12 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-000i-0000090000-530c81799c9daabdc9bf | 2016-09-12 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-014i-0968170000-ec71ee19e546088e3b05 | 2016-09-12 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-000j-0277960000-5b1eef16ffbc2ccd4b1e | 2021-09-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0081-0449400000-e362d306c4b151321fb6 | 2021-09-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0iki-0149200000-5b858e5700ff1d750a4e | 2021-09-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-000i-0001090000-b0a4df7c3417e82842d7 | 2021-09-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-000j-0135090000-fb91b96b3605a056f12f | 2021-09-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0apj-0229000000-23e454829ef21fbedf66 | 2021-09-24 | View Spectrum |
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| NMR | | Type | Description | | View |
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| 1D NMR | 13C NMR Spectrum (1D, 100 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 100 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 1000 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 200 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 200 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 300 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 300 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 400 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 400 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 500 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 500 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 600 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 600 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 700 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 700 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 800 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 800 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 13C NMR Spectrum (1D, 900 MHz, H2O, predicted) | | Spectrum | | 1D NMR | 1H NMR Spectrum (1D, 900 MHz, H2O, predicted) | | Spectrum | | 2D NMR | [1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, CDCl3, experimental) | | Spectrum |
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| External Links |
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| ChemSpider ID | 4444129 |
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| ChEMBL ID | CHEMBL1293 |
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| KEGG Compound ID | C02094 |
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| Pubchem Compound ID | 5280489 |
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| Pubchem Substance ID | Not Available |
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| ChEBI ID | 17579 |
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| Phenol-Explorer ID | Not Available |
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| DrugBank ID | Not Available |
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| HMDB ID | HMDB00561 |
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| CRC / DFC (Dictionary of Food Compounds) ID | JSX51-P:JSX51-P |
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| EAFUS ID | 531 |
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| Dr. Duke ID | BETA-BETA-CAROTENE|BETA-CAROTENE |
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| BIGG ID | 2264935 |
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| KNApSAcK ID | C00000919 |
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| HET ID | BCR |
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| Food Biomarker Ontology | Not Available |
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| VMH ID | Not Available |
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| Flavornet ID | Not Available |
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| GoodScent ID | Not Available |
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| SuperScent ID | Not Available |
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| Wikipedia ID | beta-Carotene |
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| Phenol-Explorer Metabolite ID | Not Available |
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| Duplicate IDS | |
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| Old DFC IDS | Not Available |
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| Associated Foods |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Biological Effects and Interactions |
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| Health Effects / Bioactivities | | Descriptor | ID | Definition | Reference |
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| Allergenic | 50904 | A substance that triggers an immune response, causing allergic reactions. Its biological role is to stimulate the immune system, but it has no therapeutic applications. Key medical uses include diagnosing allergies and developing immunotherapies to desensitize patients to specific allergens, reducing the risk of severe reactions. | DUKE | | Androgenic | | An agent that stimulates male characteristic development and maintenance by binding to androgen receptors, used therapeutically to treat conditions like hypogonadism, androgen deficiency, and certain types of anemia, as well as for hormone replacement therapy and fertility treatment. | DUKE | | Anti-acne | 50177 | An agent that reduces acne symptoms, commonly used in managing acne vulgaris by minimizing oil production, preventing clogged pores, and decreasing bacterial growth, thereby reducing inflammation and promoting healthy skin. | DUKE | | Anti-aging | 52217 | An agent that slows or reverses cellular aging, promoting youthful function. Its biological role involves protecting against oxidative stress and DNA damage. Therapeutically, it has applications in dermatology, gerontology, and regenerative medicine, with key medical uses including skin rejuvenation, reducing age-related diseases, and improving overall healthspan. | DUKE | | Anti-arthritic | 52217 | An agent that reduces joint inflammation and alleviates symptoms of arthritis, commonly used in managing rheumatoid arthritis, osteoarthritis, and other inflammatory joint disorders, to improve mobility and quality of life. | DUKE | | Anti-asthmatic | 49167 | An agent that relieves bronchospasm and inflammation, commonly used to manage asthma symptoms, chronic obstructive pulmonary disease (COPD), and other respiratory disorders, improving lung function and overall respiratory health. | DUKE | | Anti-cancer | 35610 | An agent that inhibits the growth and proliferation of cancer cells, used to treat and manage various types of cancer, including chemotherapy, targeted therapy, and immunotherapy, to reduce tumor size, prevent metastasis, and improve patient survival. | DUKE | | Anti carcinomic | 35610 | An agent that inhibits the growth and proliferation of cancer cells, playing a crucial role in cancer prevention and treatment. Therapeutically, it is used to manage and treat various types of cancer, reducing tumor size and slowing disease progression, with key medical uses in oncology and chemotherapy. | DUKE | | Anti-cervicaldysplasic | 52217 | An agent that prevents or treats cervical dysplasia, a precancerous condition. It helps maintain normal cell growth, reducing the risk of cervical cancer. Therapeutically, it is used to manage abnormal cell changes in the cervix, often caused by HPV infection, and is a key component in cervical cancer prevention and treatment strategies. | DUKE | | Anti coronary | 52217 | An agent that reduces the risk of coronary artery disease, lowering blood pressure and cholesterol levels. It helps prevent heart attacks, strokes, and other cardiovascular events, commonly used in managing hypertension, hyperlipidemia, and atherosclerosis. | DUKE | | Anti hyperkeratotic | | An agent that relieves severe flaking and cracking of the skin, reducing hyperkeratosis by inhibiting excessive skin cell growth. Therapeutically, it's used to treat skin conditions like eczema, psoriasis, and ichthyosis, promoting smoother skin and reducing discomfort. | DUKE | | Anti ichythyotic | | An agent that reduces or alleviates itching sensations, commonly used in managing pruritic conditions such as eczema, psoriasis, and dermatitis, providing therapeutic relief from itchiness and discomfort. | DUKE | | Anti leukoplakic | | An agent that treats leukoplakia, characterized by white patches in the oral cavity, gastrointestinal tract, urinary tract, and genitals, reducing abnormal cell growth and promoting mucosal healing, commonly used in managing precancerous lesions and oral mucosal disorders. | DUKE | | Anti lipoperoxidant | | An agent that prevents peroxidation of lipids, reducing oxidative stress and cell damage. Its biological role involves protecting cell membranes from degradation. Therapeutically, it has applications in managing conditions related to oxidative stress, with key medical uses including neuroprotection, anti-inflammation, and antioxidant therapy. | DUKE | | Anti-lupus | 52217 | An agent that suppresses the immune system, reducing inflammation and autoimmune responses, commonly used to manage systemic lupus erythematosus (SLE) and other autoimmune disorders. | DUKE | | Anti-maculitic | | An agent that reduces macular inflammation, commonly used in managing age-related macular degeneration and diabetic macular edema, promoting vision preservation and reducing disease progression. | DUKE | | Anti-mastitic | | An agent that treats mastitis, reducing inflammation and infection in breast tissue, commonly caused by S. aureus in nursing mothers, promoting healing and relieving symptoms. | DUKE | | Anti-mutagenic | | An agent that interferes with the mutagenicity of a substance, preventing DNA damage and mutations. Its biological role is to protect cells from genetic alterations, and it has therapeutic applications in cancer prevention and treatment, as well as key medical uses in reducing the risk of genetic disorders and birth defects. | DUKE | | Anti-oxidant | 22586 | An agent that neutralizes free radicals, reducing oxidative stress and cell damage. Its biological role involves protecting cells from harm, and it has therapeutic applications in managing chronic diseases, such as cancer, diabetes, and neurodegenerative disorders, with key medical uses including anti-aging, anti-inflammatory, and cardio protective effects. | DUKE | | Anti-ozenic | | An agent that reduces or prevents ozone-induced damage, commonly used in managing respiratory disorders, such as asthma and chronic obstructive pulmonary disease (COPD), by mitigating oxidative stress and inflammation in the lungs. | DUKE | | Anti-papillomic | 22587 | An agent that targets and inhibits the formation of papillomas, reducing the growth of abnormal cells. Therapeutically, it is used to treat and prevent human papillomavirus (HPV) related diseases, such as cervical cancer and genital warts, by boosting the immune system to fight off the virus. | DUKE | | Anti photophobic | 52217 | An agent that reduces light sensitivity, commonly used in managing photophobia-related conditions such as migraines, headaches, and eye disorders, promoting comfort and relief in individuals with abnormal sensitivity to light. | DUKE | | Anti-pityriasic | | An agent that relieves symptoms of skin diseases, such as pityriasis, characterized by fine, branny scales, reducing inflammation and itching, commonly used in treating conditions like seborrheic dermatitis and psoriasis. | DUKE | | Anti premenstrual syndrome | 52217 | An agent that alleviates symptoms of premenstrual syndrome (PMS), reducing physical and emotional discomfort. Its biological role involves regulating hormonal fluctuations, and its therapeutic applications include managing mood swings, bloating, and breast tenderness. Key medical uses include treating PMS, premenstrual dysphoric disorder (PMDD), and other menstrual-related disorders. | DUKE | | Anti-porphyric | | An agent that lowers porphyrin levels by catalyzing consuming reactions, used to manage porphyria disorders, reducing symptoms such as abdominal pain and neurological issues. | DUKE | | Anti proliferant | | An agent that prevents or inhibits cell growth and division, used therapeutically to treat cancer, manage tumor growth, and prevent restenosis after angioplasty, reducing abnormal cell proliferation. | DUKE | | Anti-psoriac | 52217 | An agent that reduces psoriasis symptoms, commonly used in managing plaque psoriasis, scalp psoriasis, and other inflammatory skin conditions, by inhibiting cell growth, reducing inflammation, and modulating the immune system. | DUKE | | Anti radicular | | An agent that relieves inflammation or irritation of the nerve root of a tooth, reducing pain and discomfort. Its biological role is to target and alleviate radicular pain, with therapeutic applications in endodontics and key medical uses in root canal treatments and tooth sensitivity management. | DUKE | | Anti-rheumatic | 52217 | An agent that reduces inflammation and alleviates symptoms of rheumatic diseases, such as arthritis. It plays a biological role in modulating the immune system and inhibiting pro-inflammatory pathways. Therapeutically, anti-rheumatics are used to manage conditions like rheumatoid arthritis, lupus, and osteoarthritis, reducing pain, swelling, and joint damage. Key medical uses include slowing disease progression and improving quality of life for patients with chronic rheumatic conditions. | DUKE | | Anti-stress | 52217 | An agent that reduces stress symptoms, commonly used in managing anxiety disorders, promoting relaxation, and mitigating the biological effects of stress on the body, such as hypertension and immune suppression, with therapeutic applications in mental health and key medical uses in cardiology and neurology. | DUKE | | Antitumor | 35610 | An agent that inhibits tumor growth and proliferation, playing a crucial role in cancer treatment. Therapeutically, antitumors are used to manage various types of cancer, including chemotherapy, targeted therapy, and immunotherapy, helping to reduce tumor size, prevent metastasis, and improve patient outcomes. | DUKE | | Anti ulcer | 49201 | An agent that reduces stomach acid and protects the mucous lining, preventing ulcer formation. It is used to treat conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome, promoting healing and relieving symptoms. | DUKE | | Anti xerophthalmic | 52217 | An agent that prevents or treats dryness of the eyes (xerophthalmia), often caused by vitamin A deficiency. It plays a biological role in maintaining corneal and conjunctival health. Therapeutically, it is used to treat night blindness, corneal ulcers, and dry eye syndrome, with key medical uses including vitamin A supplementation and ophthalmic lubricants. | DUKE | | Cancer preventive | 35610 | An agent that inhibits the development and progression of cancer, reducing tumor formation and growth. It plays a biological role in blocking carcinogenic pathways, and has therapeutic applications in chemoprevention. Key medical uses include reducing the risk of cancer in high-risk individuals and preventing cancer recurrence. | DUKE | | Chemopreventive | 35610 | An agent that prevents or delays the development of cancer, reducing the risk of tumor formation and progression. It plays a biological role in inhibiting carcinogenesis, and has therapeutic applications in cancer prevention, with key medical uses including reducing the risk of colorectal, breast, and prostate cancers. | DUKE | | Colorant | 37958 | A substance that imparts color, with no inherent biological role. Therapeutically, colorants are used to enhance visual appeal and identification of medications. Medically, they are used in diagnostic imaging, such as contrast agents, and in ophthalmic applications to aid in vision correction and protection. | DUKE | | Cyclooxygenase-1 inhibitor | 50630 | An agent that blocks the activity of cyclooxygenase-1 (COX-1), reducing inflammation and pain. Therapeutically, it is used to manage conditions like arthritis, and as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain, fever, and inflammation, while minimizing gastrointestinal side effects. | DUKE | | Cyclooxygenase-2 inhibitor | 50629 | An agent that blocks the activity of cyclooxygenase-2 (COX-2), reducing inflammation and pain. Therapeutically, it is used to manage conditions such as arthritis, menstrual cramps, and other inflammatory disorders, providing relief from symptoms with reduced gastrointestinal side effects compared to non-selective NSAIDs. | DUKE | | Gastroprotective | 55324 | An agent that protects the stomach and intestinal lining, reducing inflammation and preventing damage. It has therapeutic applications in managing gastrointestinal disorders, such as ulcers and gastritis, and is commonly used to prevent NSAID-induced stomach damage and treat acid reflux disease. | DUKE | | Immunostimulant | 50847 | An agent that stimulates the immune system, enhancing its response to infections and diseases. Therapeutically, it boosts the body's natural defenses, commonly used to treat immunodeficiency disorders, prevent infections, and support cancer treatment, as well as manage chronic conditions like hepatitis and HIV. | DUKE | | Interferon-synergist | | An agent that enhances the effects of interferons, boosting the immune system's response to infections and diseases. It has therapeutic applications in treating viral infections, cancers, and autoimmune disorders, with key medical uses including antiviral and anticancer therapies. | DUKE | | Mucogenic | | An agent that promotes mucus formation, playing a biological role in protecting and lubricating epithelial surfaces. Therapeutically, mucogenics are used to treat dryness and irritation in respiratory, gastrointestinal, and ocular systems, with key medical applications in managing conditions like dry eye, coughs, and gastrointestinal ulcers. | DUKE | | Phagocytotic | | An agent that engulfs and internalizes solid particles or cells through phagocytosis, playing a key role in immune defense. Therapeutically, it aids in removing pathogens and debris, with medical applications in treating infections and inflammatory disorders. | DUKE | | Prooxidant | | An agent that induces oxidative stress by generating reactive oxygen species (ROS) or inhibiting antioxidant systems, playing a role in cell damage and disease progression. Therapeutically, prooxidants have applications in cancer treatment, as they can selectively kill cancer cells. Key medical uses include cancer therapy and antimicrobial treatments. | DUKE | | Thymoprotective | | An agent that protects the thymus, supporting immune function and development. It alleviates or prevents thymus-related conditions, with therapeutic applications in immunodeficiency and autoimmune disorders, and key medical uses in treating thymus-related diseases and enhancing immune system health. | DUKE | | Ubiquiot | | An antioxidant that protects cells from damage, playing a crucial role in energy production. Therapeutically, it has applications in managing neurodegenerative and cardiovascular diseases, with key medical uses including reducing oxidative stress and improving mitochondrial function. | DUKE |
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| Enzymes | Not Available |
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| Pathways | |
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| Metabolism | Not Available |
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| Biosynthesis | Not Available |
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| Organoleptic Properties |
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| Flavours | Not Available |
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| Files |
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| MSDS | show |
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| References |
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| Synthesis Reference | Not Available |
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| General Reference | Not Available |
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| Content Reference | — Saxholt, E., et al. 'Danish food composition databank, revision 7.' Department of Nutrition, National Food Institute, Technical University of Denmark (2008). — U.S. Department of Agriculture, Agricultural Research Service. 2008. USDA National Nutrient Database for Standard Reference, Release 21. Nutrient Data Laboratory Home Page. — Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004). — Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.
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