Record Information |
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Version | 1.0 |
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Creation date | 2010-04-08 22:14:51 UTC |
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Update date | 2019-11-26 03:18:36 UTC |
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Primary ID | FDB020188 |
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Secondary Accession Numbers | |
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Chemical Information |
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FooDB Name | Arabinogalactan |
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Description | Emulsifier, stabiliser
Approximately one of the three arabinosyl chains attached to the galactan chain contains succinyl groups. Although one succinyl group is most common, up to three succinyl groups per released arabinan fragment can be found on oligo-arabinans. However, arabinan fragments substituted with GalNH2 are not succinylated. Importantly, in the case of M. tuberculosis, and most likely in all slow growers, both positive charge (protonated GalNH2 as GalNH3+) and negative charge (succinyl) are present in the middle regions of the arabinan, specifically at O-2 of the inner 3,5-?-D-Araf units. The succinyl residues are on the non-mycolylated chain. Recently a complete primary model of arabinogalactan has been proposed.; Arabinogalactan is a biopolymer consisting of arabinose and galactose monosaccharides. Two classes of arabinogalctans are found in nature: plant arabinogalactan and microbial arabinogalactan. In plants, it is a major constituents of many gums, including gum arabic, gum gutti and so on. It occasionally attached to proteins and the resulted proteoglycan functions as signaling molecules betweens cells as well as glue to seal wounded part of plants.; The microbial arabinogalactan is a major structural component of the mycobacterial cell wall. Both the arabinose and galactose are solely in the furanose configuration. The galactan portion of the microbial arabinogalactan is linear, consisting of approximately 30 units with alternating ?-(1-5) and ?-(1-6) glycosidic linkages. The arabinan chain, which consist of about 30 residues, are attached at three branch points within the galactan chain (believed to be at residues 8, 10 and 12).The arabinan portion of the polymer is a complex branched structure, usually capped with mycolic acids. The arabinan glycosidic linkages are ?-(1-3), ?-(1-5), and ?-(1-2).; The non-reducing end of arabinogalactan is covalently attached to the mycolic acids of the outer membrane. The hydrophobicity of mycolic acids is a barrier to drug entry. Additionally, the mycolyl arabinogalactan peptidiglycan is responsible for aspects of disease pathogenesis and much of the antibody response in infections. The mycolyl substituents are selectively and equally distributed on the 5-hydroxyl functions of terminal- and the penultimate 2-linked Araf residues. The mycolyl residues are clustered in groups of four on the non reducing terminal pentaarabinosyl unit (?-Araf-(1?2)-?-Araf)2-3,5-?-Araf. Thus, the major part (66%) of the pentaarabinosyl units are substituted by mycolic acids, leaving the unsubstituted minor region (33%), that is available for interaction with the immune system. |
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CAS Number | 93-04-9 |
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Structure | |
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Synonyms | Synonym | Source |
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2-Methoxy-naphthalene | ChEMBL, HMDB | 2-Naphthol methyl ether | HMDB | 2-Naphthyl methyl ether | HMDB | b-Naphthyl methyl ether | HMDB | beta -Methoxynaphthalene | HMDB | beta -Naphthol methyl ether | HMDB | beta -Naphthyl methyl ether | HMDB | beta-Methoxynaphthalene | HMDB | beta-Naphthol mether ether | HMDB | beta-Naphthol methyl ether | HMDB | beta-Naphthyl methyl ether | HMDB | Jara jara | HMDB | Methyl 2-naphthyl ether | HMDB | Methyl beta -naphthyl ether | HMDB | Methyl beta-naphthyl ether | HMDB | Nerolin | HMDB | Nerolin yara yara | HMDB | Yara yara | HMDB | Yara-yara | HMDB | Yura yara | HMDB | Arabino galactan | biospider | Arabinogalactoglycan | biospider | D-Galacto-L-arabinan | db_source | FEMA 3254 | db_source | Galacto-l-arabinan, l- | biospider | Galactoarabinan | biospider | Larch gum | db_source |
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Predicted Properties | |
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Chemical Formula | C11H10O |
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IUPAC name | 2-methoxynaphthalene |
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InChI Identifier | InChI=1S/C11H10O/c1-12-11-7-6-9-4-2-3-5-10(9)8-11/h2-8H,1H3 |
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InChI Key | LUZDYPLAQQGJEA-UHFFFAOYSA-N |
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Isomeric SMILES | COC1=CC2=C(C=CC=C2)C=C1 |
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Average Molecular Weight | 158.1965 |
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Monoisotopic Molecular Weight | 158.073164942 |
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Classification |
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Description | Belongs to the class of organic compounds known as naphthalenes. Naphthalenes are compounds containing a naphthalene moiety, which consists of two fused benzene rings. |
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Kingdom | Organic compounds |
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Super Class | Benzenoids |
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Class | Naphthalenes |
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Sub Class | Not Available |
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Direct Parent | Naphthalenes |
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Alternative Parents | |
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Substituents | - Naphthalene
- Anisole
- Alkyl aryl ether
- Ether
- Organic oxygen compound
- Hydrocarbon derivative
- Organooxygen compound
- Aromatic homopolycyclic compound
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Molecular Framework | Aromatic homopolycyclic compounds |
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External Descriptors | Not Available |
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Ontology |
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Disposition | Route of exposure: Biological location: Source: |
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Role | Biological role: |
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Physico-Chemical Properties |
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Physico-Chemical Properties - Experimental | Property | Value | Reference |
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Physical state | Not Available | |
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Physical Description | Not Available | |
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Mass Composition | Not Available | |
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Melting Point | Not Available | |
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Boiling Point | Not Available | |
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Experimental Water Solubility | Not Available | |
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Experimental logP | Not Available | |
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Experimental pKa | Not Available | |
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Isoelectric point | Not Available | |
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Charge | Not Available | |
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Optical Rotation | Not Available | |
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Spectroscopic UV Data | Not Available | |
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Density | Not Available | |
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Refractive Index | Not Available | |
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Spectra |
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Spectra | |
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EI-MS/GC-MS | Type | Description | Splash Key | View |
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GC-MS | 2-Methoxynaphthalene, non-derivatized, GC-MS Spectrum | splash10-0aor-1900000000-1c20535f4a69bcfc204d | Spectrum | GC-MS | 2-Methoxynaphthalene, non-derivatized, GC-MS Spectrum | splash10-0aor-2900000000-84b3e0628bd2f527ae1b | Spectrum | GC-MS | 2-Methoxynaphthalene, non-derivatized, GC-MS Spectrum | splash10-0aor-1900000000-1c20535f4a69bcfc204d | Spectrum | GC-MS | 2-Methoxynaphthalene, non-derivatized, GC-MS Spectrum | splash10-0aor-2900000000-84b3e0628bd2f527ae1b | Spectrum | Predicted GC-MS | 2-Methoxynaphthalene, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-0a4i-0900000000-ccf8c9adde7dafebe859 | Spectrum | Predicted GC-MS | 2-Methoxynaphthalene, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
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MS/MS | Type | Description | Splash Key | View |
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Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0a4i-0900000000-b1ad72aed00419e872cd | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0a4i-0900000000-6482b5288c37c635e9fa | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0fbc-0900000000-67946d6a51ce2f911531 | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0a4i-0900000000-7f5929f25f4a347a587f | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0a4i-0900000000-ad2ccbae645853cd88b6 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-0900000000-99f2122554947d468964 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0a4i-0900000000-8c3e029a7181e41a403f | 2021-09-22 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0a4i-0900000000-8c3e029a7181e41a403f | 2021-09-22 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-004i-0900000000-6d505baa78133ad36986 | 2021-09-22 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0a4i-0900000000-05067fadfe9b6e821555 | 2021-09-22 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0a4i-0900000000-6a99e14fce415d83a770 | 2021-09-22 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-004i-3900000000-b02e217f39d8ec711ef4 | 2021-09-22 | View Spectrum |
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NMR | Not Available |
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External Links |
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ChemSpider ID | 6852 |
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ChEMBL ID | CHEMBL195857 |
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KEGG Compound ID | C00569 |
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Pubchem Compound ID | 7119 |
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Pubchem Substance ID | Not Available |
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ChEBI ID | Not Available |
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Phenol-Explorer ID | Not Available |
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DrugBank ID | Not Available |
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HMDB ID | HMDB32861 |
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CRC / DFC (Dictionary of Food Compounds) ID | MLO07-X:MLO07-X |
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EAFUS ID | 246 |
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Dr. Duke ID | ARABINOGALACTAN |
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BIGG ID | Not Available |
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KNApSAcK ID | Not Available |
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HET ID | Not Available |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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Flavornet ID | Not Available |
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GoodScent ID | Not Available |
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SuperScent ID | Not Available |
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Wikipedia ID | Arabinogalactan |
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Phenol-Explorer Metabolite ID | Not Available |
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Duplicate IDS | Not Available |
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Old DFC IDS | Not Available |
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Associated Foods |
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Food | Content Range | Average | Reference |
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Food | | | Reference |
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Biological Effects and Interactions |
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Health Effects / Bioactivities | Descriptor | ID | Definition | Reference |
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Anti complementary | | A substance that diminishes or abolishes the action of a complement, playing a role in regulating the immune system. Therapeutically, it's used to prevent excessive inflammation and tissue damage. Key medical uses include treating autoimmune disorders, transplant rejection, and inflammatory diseases. | DUKE | Anti leishmanic | 33281 | An agent that treats Leishmaniasis, a parasitic disease caused by Leishmania parasites. It kills or inhibits the growth of these parasites, reducing symptoms and preventing disease progression. Therapeutically, anti-leishmanics are used to manage cutaneous, visceral, and mucocutaneous Leishmaniasis, often in combination with other treatments. Key medical uses include treating infected individuals, particularly in endemic regions. | DUKE | Immunostimulant | 50847 | An agent that stimulates the immune system, enhancing its response to infections and diseases. Therapeutically, it boosts the body's natural defenses, commonly used to treat immunodeficiency disorders, prevent infections, and support cancer treatment, as well as manage chronic conditions like hepatitis and HIV. | DUKE | Interferonogenic | | An agent that stimulates interferon production, enhancing immune response to pathogens, with therapeutic applications in treating viral infections and cancers, and key medical uses in immunotherapy and antiviral treatments. | DUKE | Mitogenic | | A substance that stimulates cell division, triggering mitosis, with roles in growth, development, and tissue repair. Therapeutically, mitogens are used to enhance wound healing, tissue regeneration, and in cancer treatments to stimulate immune response. Key medical uses include promoting cell growth in damaged tissues and supporting hematopoiesis. | DUKE | Phagocytotic | | An agent that engulfs and internalizes solid particles or cells through phagocytosis, playing a key role in immune defense. Therapeutically, it aids in removing pathogens and debris, with medical applications in treating infections and inflammatory disorders. | DUKE |
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Enzymes | Not Available |
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Pathways | Not Available |
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Metabolism | Not Available |
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Biosynthesis | Not Available |
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Organoleptic Properties |
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Flavours | Not Available |
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Files |
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MSDS | Not Available |
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References |
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Synthesis Reference | Not Available |
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General Reference | Not Available |
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Content Reference | — Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).
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