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Showing Health Effect Immunostimulant

Identification
NameImmunostimulant
ChEBI ID50847
ChEBI Nameimmunological adjuvant
ChEBI DefinitionA substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
Associations
Compounds
CompoundReference TypeReference
AlliinDATABASEDUKE
Gallic acidDATABASEDUKE
GossypolDATABASEDUKE
Protocatechuic acidDATABASEDUKE
Chinese tanninDATABASEDUKE
InulinDATABASEDUKE
L-Ascorbic acidDATABASEDUKE || 10.1002/fsn3.3993 || PMID: 38726460
(-)-ArctigeninDATABASEDUKE
EupatorinDATABASEDUKE
AllantoinDATABASEDUKE
Theaflavin 3,3'-digallateDATABASEDUKE
Rosmarinic acidDATABASEDUKE
Caffeic acidDATABASEDUKE
CatechinDATABASEDUKE
EpicatechinDATABASEDUKE
Chlorogenic acidDATABASEDUKE
DaphnetinDATABASEDUKE
AnetholeDATABASEDUKE
PhosphorusDATABASEDUKE
ZincDATABASEDUKE
MelatoninDATABASEDUKE
LysolecithinDATABASEDUKE
Vitamin EDATABASEDUKE || 10.3390/pathogens10080980 || PMID: 34451443
PlumbaginDATABASEDUKE
EstrogenDATABASEDUKE
TocopherolsDATABASEDUKE
SyringinDATABASEDUKE
GenisteinDATABASEDUKE
Arachidonic acidDATABASEDUKE
2H-1-Benzopyran-2-oneDATABASEDUKE
Chicoric acidDATABASEDUKE
AllicinDATABASEDUKE || 10.3390/molecules26030574 || PMID: 33499159
Di-2-propenyl disulfide, 9CIDATABASEDUKE
CurcuminDATABASEDUKE
TomatineDATABASEDUKE
alpha-Linolenic acidDATABASEDUKE
S-AllylcysteineDATABASEDUKE
Ferulic acidDATABASEDUKE
Coenzyme QDATABASEDUKE
SeleniumDATABASEDUKE || 10.3390/pathogens10080980 || PMID: 34451443
EmodinDATABASEDUKE
Folic acidDATABASEDUKE
beta-CaroteneDATABASEDUKE
BenzaldehydeDATABASEDUKE
SqualeneDATABASEDUKE
AstragalinDATABASEDUKE || 10.3390/molecules27155011 || PMID: 35956963
Epicatechin 3-gallateDATABASEDUKE
Epigallocatechin 3-gallateDATABASEDUKE
ArabinogalactanDATABASEDUKE
Ukonan ADATABASEDUKE
L-IsoleucineARTICLE10.1111/jvim.17217 || PMID: 39466655
5-Isopropyl-2-methylphenolARTICLE10.1007/s11250-023-03620-5 || PMID: 37202581
cinnamaldehydeARTICLE10.3389/fcimb.2025.1647320 || PMID: 41031111
2-Isopropyl-5-methylphenolARTICLE10.1007/s11250-023-03620-5 || PMID: 37202581
trans-5-O-caffeoyl-D-quinateARTICLE10.3390/ph15121502 || PMID: 36558953
3-Phenyl-2-propenalARTICLE10.3389/fcimb.2025.1647320 || PMID: 41031111
Phytochelatin AARTICLE10.3390/biomedicines13061311 || PMID: 40564030
laurateARTICLE10.5455/OVJ.2025.v15.i8.21 || PMID: 41035991
Quercetin 3-rutinosideARTICLE10.3390/antiox15010093 || PMID: 41596151
ChitosanARTICLE10.1016/j.heliyon.2023.e18197 || PMID: 37519647
p-Menthan-3-olARTICLE10.3390/plants7040079 || PMID: 30248993
methylglyoxalARTICLE10.1177/1178633717702869 || PMID: 28469409
(Z,Z)-9,12-Octadecadienoic acidARTICLE10.3390/ani10030464 || PMID: 32168766
alpha-TocopherolARTICLE10.1002/fsn3.3993 || PMID: 38726460
Vanillic acidARTICLE10.3390/molecules25092070 || PMID: 32365518
Ursolic acidARTICLE10.3390/nu14132619 || PMID: 35807800
ApigeninARTICLE10.3390/molecules26164969 || PMID: 34443561
BerberineARTICLE10.1007/s13659-020-00281-x || PMID: 33174095
GlycyrrhizinARTICLE10.1155/2013/849412 || PMID: 23984091
RetinolARTICLE10.1002/fsn3.3993 || PMID: 38726460
Oleanolic acidARTICLE10.3390/nu14132619 || PMID: 35807800
(2E,7R,11R)-2-Phyten-1-olARTICLE10.52225/narra.v4i1.321 || PMID: 38798837
(+)-ValineARTICLE10.3390/nu11061303 || PMID: 31181780
beta-GlucanARTICLE10.3389/fimmu.2022.960554 || PMID: 35935938 || 10.1186/s12866-024-03473-4
(R)-SulforaphaneARTICLE10.3390/antiox13101173 || PMID: 39456427
L-ascorbateARTICLE10.5455/javar.2022.i571 || PMID: 35445121
BisdemethoxycurcuminARTICLE10.1186/1471-2202-9-S2-S13 || PMID: 19090986
ErgosterolARTICLE10.3390/molecules28134907 || PMID: 37446570
β-D-fructofuranoseARTICLE10.1016/j.heliyon.2024.e32342 || PMID: 32010129
(2R,3S)-2-hydroxy-3-[(E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoyl]oxy-2-[(4-hydroxyphenyl)methyl]butanedioic acidARTICLE10.3390/plants11233333 || PMID: 36501372
ChitinARTICLE10.1186/s42523-024-00316-5 || PMID: 38812012
L-LeucineARTICLE10.1111/jvim.17217 || PMID: 39466655
Cucurbitacin EARTICLE10.3390/molecules29184377 || PMID: 39339372
MannanARTICLE10.3390/foods13101567 || PMID: 38790867
AcetaldehydeARTICLE10.3389/fnut.2022.1025897
MelibioseARTICLE10.1021/acs.jafc.8b00369 || PMID: 29561614
IsoscopoletinARTICLE10.1007/s13668-022-00437-w || PMID: 36125704
LPS-o-antigenARTICLE10.3390/microorganisms7120613 || PMID: 31775350
N-acetyl-β-D-glucosamineARTICLE10.1002/2211-5463.13694
SpermidineARTICLE10.3390/metabo13030342 || PMID: 36984782
D-ApioseARTICLE10.3390/plants12040937 || PMID: 36840285
NutrientsNot Available