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Showing Health Effect Hepatotoxic

Identification
NameHepatotoxic
ChEBI ID50908
ChEBI Namehepatotoxic agent
ChEBI DefinitionA role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals.
Associations
Compounds
CompoundReference TypeReference
GossypolDATABASEDUKE
EthanolDATABASEDUKE || 10.3390/nu14224752 || PMID: 36432440
Protocatechuic acidDATABASEDUKE
Nicotinic acidDATABASEDUKE
Chinese tanninDATABASEDUKE
LycopsamineDATABASEDUKE
AnetholeDATABASEDUKE
Isopropyl acetateDATABASEDUKE
AmabilineDATABASEDUKE
IntermedineDATABASEDUKE
SupinineDATABASEDUKE
GuanidineDATABASEDUKE
SafroleDATABASEDUKE
ApioleDATABASEDUKE
2H-1-Benzopyran-2-oneDATABASEDUKE
AllicinDATABASEDUKE
ImperatorinDATABASEDUKE
(R)-p-Menth-4(8)-en-3-oneDATABASEDUKE
IsopulegoneDATABASEDUKE
MyristicinDATABASEDUKE || 10.1016/j.jsps.2024.102067 || PMID: 38690209
MenthofuranDATABASEDUKE
PunicalaginDATABASEDUKE || 10.1089/jmf.2019.4411 || PMID: 31718395
PunicalinDATABASEDUKE
5-Isopropyl-2-methylphenolARTICLE10.3390/ph18020267 || PMID: 40006079
all-trans-lycopeneARTICLE10.22038/IJBMS.2020.43060.10123 || PMID: 32489556
trans-resveratrolARTICLE10.3389/fimmu.2022.965954 || PMID: 36405693
Gallic acidARTICLE10.2147/DDDT.S344247 || PMID: 35965961
2-Isopropyl-5-methylphenolARTICLE10.3390/ph17081094 || PMID: 39204199
EugenolARTICLE10.15430/JCP.2014.19.4.288 || PMID: 25574464
KaempferolARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
SeleniumARTICLE10.3390/plants12122278 || PMID: 37375903
Syringic acidARTICLE10.3389/fnut.2022.1052818 || PMID: 36704792
Rosmarinic acidARTICLE10.3390/plants13040491 || PMID: 38498430
alpha-CrocinARTICLE10.7717/peerj.15535 || PMID: 37404473
laurateARTICLE10.1016/j.heliyon.2023.e21267 || PMID: 37908709
Quercetin 3-rutinosideARTICLE10.1016/j.fochx.2025.103158 || PMID: 41211158 || 10.3390/plants10040700
NaringinARTICLE10.3390/nu9020102 || PMID: 28157162
CapsaicinARTICLE10.5455/OVJ.2025.v15.i9.9 || PMID: 41200297
(S)-NaringeninARTICLE10.22038/IJBMS.2020.43060.10123 || PMID: 32489556 || 10.3390/nu9020102
CitralARTICLE10.3390/molecules29184365
ShogaolsARTICLE10.1186/s13098-019-0407-0 || PMID: 30805033
(±)-CatechinARTICLE10.1371/journal.pone.0299238 || PMID: 38483871
SilibininARTICLE10.3390/molecules23071705 || PMID: 30002357
Feruloyl isoquercitrin 4'-glucosideARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
alpha-TocopherolARTICLE10.3390/toxics11040368 || PMID: 37112594
palmitateARTICLE10.3389/fchem.2024.1487084 || PMID: 39512543
Luteolin 7-rhamnosylglucosideARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
Ursolic acidARTICLE10.3390/plants13040491 || PMID: 38498430 || 10.1016/j.heliyon.2024.e30547
CurcuminARTICLE10.1016/j.bbrep.2017.06.002 || PMID: 28955769
(+)-taxifolinARTICLE10.3389/fphar.2023.1173855 || PMID: 37261284
(R)-LimoneneARTICLE10.3390/foods11081121 || PMID: 35454708
2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triolARTICLE10.1007/s10068-022-01069-0 || PMID: 35345441
ApigeninARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
PiperineARTICLE10.3389/fphar.2021.780330 || PMID: 34776989
Ochratoxin AARTICLE10.3389/fvets.2022.944891 || PMID: 36118355 || 10.3390/molecules28031442
GlycyrrhizinARTICLE10.3389/fvets.2025.1628457 || PMID: 40727271
EucalyptolARTICLE10.2903/j.efsa.2021.6548 || PMID: 33968248
GeraniolARTICLE10.3390/molecules29010279 || PMID: 38202861
AstragalinARTICLE10.1016/j.jfda.2014.10.002 || PMID: 28911387
AflatoxinARTICLE10.1590/S1517-838220090001000024 || PMID: 32765435
IsoestragoleARTICLE10.1021/acs.jmedchem.2c01406 || PMID: 36858050
L-Ascorbic acidARTICLE10.3390/plants12122278 || PMID: 37375903
Oleanolic acidARTICLE10.1186/s12906-023-04041-5 || PMID: 37393246
(+)-pulegoneARTICLE10.3390/antibiotics10101266 || PMID: 34680848
5-Hydroxymethyl-2-furancarboxaldehydeARTICLE10.3389/fnut.2021.645416 || PMID: 34095186
CaneineARTICLE10.3390/foods11244038 || PMID: 36553779
IsovitexinARTICLE10.4103/0973-1296.176111 || PMID: 27041853
Luteolin 7-glucosideARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
1-Methoxy-4-(2-propenyl)benzeneARTICLE10.1021/acs.jmedchem.2c01406 || PMID: 36858050 || 10.3390/foods14020294
CrocetinARTICLE10.2147/DDDT.S247947 || PMID: 32546959
(S,E)-ZearalenoneARTICLE10.3390/toxins17020052 || PMID: 39998069 || 10.1016/j.etp.2010.12.012
ChrysinARTICLE10.23750/abm.v90i4.7534 || PMID: 31910181
AloeemodinARTICLE10.1016/j.heliyon.2022.e10907 || PMID: 36247124
4-Isopropylbenzoic acidARTICLE10.31557/APJCP.2024.25.10.3515 || PMID: 39471017
Linalyl acetateARTICLE10.1007/s11064-024-04239-0 || PMID: 39298035
stearateARTICLE10.3389/fchem.2024.1487084 || PMID: 39512543
3,4-DihydroxybenzaldehydeARTICLE10.2147/DDDT.S76336 || PMID: 25733819
EmodinARTICLE10.2147/DDDT.S557114 || PMID: 41158982 || 10.1002/ame2.12474
L-ascorbateARTICLE10.22038/IJBMS.2020.43060.10123 || PMID: 32489556
IsoorientinARTICLE10.4103/0973-1296.176111 || PMID: 27041853
ErgosterolARTICLE10.3390/foods12132529 || PMID: 37444267
PelargonidinARTICLE10.3389/fphar.2017.00868 || PMID: 29230174
Kaempferol 3-rutinosideARTICLE10.1016/j.jfda.2014.10.002 || PMID: 28911387
2-FurancarboxaldehydeARTICLE10.17113/ftb.63.01.25.8605 || PMID: 40322284
CitrininARTICLE10.3390/md21030168 || PMID: 36976217
RheinARTICLE10.2147/DDDT.S476273 || PMID: 39403095
AesculetinARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
2,6-Di-tert-butyl-4-methylphenolARTICLE10.3390/microorganisms11051157 || PMID: 37317130 || 10.3390/molecules28145302
FucosterolARTICLE10.3390/md18110564 || PMID: 33218066
Geranyl acetateARTICLE10.1007/s11064-024-04239-0 || PMID: 39298035
(S)-CarvoneARTICLE10.3390/molecules29184365 || PMID: 39339360
dihydromyricetinARTICLE10.1186/s13020-024-00906-0 || PMID: 38439080
CadmiumARTICLE10.1002/fsn3.71254 || PMID: 41323831
Carbon tetrachlorideARTICLE10.3892/etm.2019.7886 || PMID: 31572524
AcrylamideARTICLE10.3389/fnut.2023.1080825 || PMID: 36814509
Aflatoxin M1ARTICLE10.14202/vetworld.2022.91-101 || PMID: 35369598
(-)-GossypolARTICLE10.1155/2014/231635 || PMID: 24895646
2,2'-Bis(4-hydroxyphenyl)propaneARTICLE10.3390/toxics12120864 || PMID: 39771079
UmbelliferoneARTICLE10.1016/j.jsps.2023.101708 || PMID: 37564748
L-carnitineARTICLE10.3390/plants12122278 || PMID: 37375903
ArecolineARTICLE10.3390/foods13233825 || PMID: 39682896
ElemicinARTICLE10.1021/acs.chemrestox.9b00112 || PMID: 31468958
Kaempferol 3-rhamnosideARTICLE10.1016/j.fbio.2022.101977 || PMID: 36059903
ChloroformARTICLE10.7759/cureus.33430 || PMID: 36628398
Ursolic acid (2-alpha-hydroxy-)ARTICLE10.3390/foods11244038 || PMID: 36553779
AspartameARTICLE10.3390/plants11111394 || PMID: 35684166
ChrysophanolARTICLE10.1002/ame2.12474 || PMID: 39439047
GermacroneARTICLE10.3390/biom14040387 || PMID: 38672405
AcetaldehydeARTICLE10.3389/fnbeh.2023.1057262 || PMID: 36865774
ApiumetrinARTICLE10.3390/foods8120630 || PMID: 31810218
LiensinineARTICLE10.1371/journal.pone.0294769 || PMID: 38175855
3-MethylcyclopentadecanoneARTICLE10.1186/s13020-021-00457-8 || PMID: 34147113
T2 ToxinARTICLE10.3390/toxins12100627 || PMID: 33008105
ImidaclopridARTICLE10.3390/toxics11070569 || PMID: 37505536
Deoxycholic acidARTICLE10.1016/j.aninu.2025.01.015 || PMID: 41170398
5-(4-Acetoxy-3-oxo-1-butynyl)-2,2'-bithiopheneARTICLE10.1007/s13659-018-0175-9 || PMID: 29959744
ArseniteARTICLE10.2147/DDDT.S247947 || PMID: 32546959
Chrysoeriol 7-glucosideARTICLE10.1371/journal.pone.0259757 || PMID: 35421091
Sodium hydrogen carbonateARTICLE10.1007/s10695-025-01532-9 || PMID: 40676362
alpha-Terpinyl acetateARTICLE10.3390/antiox11101911 || PMID: 36290633
MethyleugenolARTICLE10.1021/acs.jmedchem.2c01406 || PMID: 36858050
Calcium chloride (CaCl2)ARTICLE10.1007/s10695-025-01532-9 || PMID: 40676362
PaeonolARTICLE10.3389/fphar.2016.00174 || PMID: 27378929
IsoliensinineARTICLE10.1371/journal.pone.0294769 || PMID: 38175855
DeoxynivalenolARTICLE10.3390/toxins17020052 || PMID: 39998069
AcetaminophenARTICLE10.3389/fphar.2020.581840 || PMID: 33071794 || 10.3389/fphar.2017.00982
GummosininARTICLE10.3390/foods11244038 || PMID: 36553779
PolyacrylamideARTICLE10.4254/wjh.v17.i10.109807 || PMID: 41179736
Potassium bromate(V) (KBrO3)ARTICLE10.1016/j.toxrep.2023.02.007 || PMID: 36876028
all-trans-Retinoic acidARTICLE10.3390/antiox12040903 || PMID: 37107278
(-)-Kaur-16-en-19-oic acidARTICLE10.1002/fsn3.70723 || PMID: 41000259
NutrientsNot Available